A Study to Verify the Efficacy of YM177 (Celecoxib) in Postoperative Pain Patients
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
Aim of the study is to compare efficacy and safety of YM177 with placebo and etodolac in patients with postoperative pain.
Condition or disease
Post Operative Pain
Drug: YM177Drug: etodolacDrug: Placebo
To verify the superiority to placebo and the noninferiority to etodolac of YM177 in terms of efficacy assessment in patients with postoperative pain. Also, to compare them in terms of safety assessment.
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
A Phase III Study of YM177 (Postoperative Pain) -- An Etodolac- and Placebo-controlled, Multicenter, Double-blind, Group Comparison Study to Verify the Efficacy of YM177 (Celecoxib) in Postoperative Pain Patients --
Study Start Date
Actual Primary Completion Date
Actual Study Completion Date
Resource links provided by the National Library of Medicine
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
20 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients with spontaneous pain within 24 hours postoperatively
The intensity of the pain:
4-categorical assessment: "Moderate pain" or "Severe pain"
VAS assessment: 45.0 mm or higher
Patients whose postoperative pain can be managed using an oral NSAID
A past history of aspirin-induced asthma
A past of ischemic heart disease, serious arrhythmia, congestive heart failure or cerebrovascular disease
Patients who undergoes the surgical procedure under general anesthesia