Total Intravenous Anaesthesia (TIVA) Versus Spinal Anaesthesia in Patients Undergoing Transurethral Prostate Resection (TURPS)

This study has been completed.
Information provided by:
Asker & Baerum Hospital Identifier:
First received: April 7, 2010
Last updated: May 5, 2010
Last verified: May 2010

Comparison of total intravenous anaesthesia with spinal anaesthesia in patients undergoing transurethral prostate resection

Condition Intervention Phase
Procedure: total intravenous anaesthesia
Procedure: spinal anaesthesia
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: TIVA Versus Spinal Anaesthesia in Patients Undergoing Transurethral Prostate Resection

Resource links provided by NLM:

Further study details as provided by Asker & Baerum Hospital:

Primary Outcome Measures:
  • patient satisfaction [ Time Frame: 4 hours ] [ Designated as safety issue: No ]
    Patient satisfaction was measured asking the patient about satisfaction with anaesthesia using a 5-point Linkert scale: totally satisfied - satisfied - neither satisfied nor dissatisfied - dissatisfied - totally dissatisfied Time frame: Start anaesthesia to end post anaesthestic care unit

Secondary Outcome Measures:
  • time in PACU [ Time Frame: 4 hours ] [ Designated as safety issue: No ]
    period in post anaesthetic care unit

Enrollment: 101
Study Start Date: January 2006
Study Completion Date: May 2009
Primary Completion Date: May 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: TIVA
Total intravenous anaesthesia (TIVA) with propofol and remifentanil
Procedure: total intravenous anaesthesia
propofol and remifentanil
Active Comparator: Spinal
Spinal anaesthesia with bupivacaine and fentanyl
Procedure: spinal anaesthesia
bupivacaine and fentanyl

Detailed Description:

Comparison of total intravenous anaesthesia with spinal anaesthesia in patients undergoing transurethral prostate resection regarding patient satisfaction and discharge time


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 18 years and older
  • signed informed consent
  • elective transurethral prostata resection

Exclusion Criteria:

  • ASA more than 3
  • kidney disease, liver disease
  • intolerance against bupivacaine, fentanyl, propofol og remifentanil
  • chronic pulmonary disease
  • dementia
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01118260

Asker & Baerum Hospital
Rud, Norway, 1309
Sponsors and Collaborators
Asker & Baerum Hospital
Study Chair: Vegard Dahl, MD, PhD Asker & Baerum Hospital
Principal Investigator: Elisabet Andersson Asker & Baerum Hospital
  More Information

No publications provided

Responsible Party: Dr. med. Vegard Dahl, Asker & Baerum Hospital, Vestre Viken HF Identifier: NCT01118260     History of Changes
Other Study ID Numbers: 2004-002672-42
Study First Received: April 7, 2010
Last Updated: May 5, 2010
Health Authority: Norway:National Committee for Medical and Health Research Ethics
Norway: Norwegian Medicines Agencies

Keywords provided by Asker & Baerum Hospital:
prostata hyperplasia
transurethral resection
spinal anaesthesia

Additional relevant MeSH terms:
Pathologic Processes
Central Nervous System Agents
Central Nervous System Depressants
Pharmacologic Actions
Physiological Effects of Drugs
Therapeutic Uses processed this record on October 09, 2015