The Relationship of PRL and Polycystic Ovary Syndrome (PCOS) in Taiwan's Women
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder of reproductive-age women. According to Rotterdam 2003 criteria: at least two of three criteria are met, hyperandrogenism, chronic anovulation, and polycystic ovary. PCOS will cause irregular menstrual cycle, infertility, acne, hirsutism, obesity, or/and metabolic syndrome, diabetes that may increase risk of cardiovascular disease.
Hyperprolactinaemia is also a common problem in reproductive aged women. Both hyperprolactinaemia and PCOS had endocrine disorder and irregular menstrual cycle. Investigators hope to collect clinical data from PCOS and prolactinemia patients followed in Wang Fang hospital for many years in endocrinological and metabolical aspects for comparison. Investigators at the same time would like to understand more about other similarities and differences between these two endocrinological dysfunction for future study.
Polycystic Ovary Syndrome
|Study Design:||Observational Model: Cohort
Time Perspective: Retrospective
|Official Title:||Relationship of Metabolic Parameters, Endocrine and Prolactin Levels in Taiwan's Women With Polycystic Ovary Syndrome and Hyperprolactinemia.|
- hyperprolactin [ Time Frame: Who visited the Reproductive Endocrinology Clinic at Taipei Medical University-Wan Fang Medical Center from April 2004 to June 2007 ] [ Designated as safety issue: No ]
|Study Start Date:||May 2009|
|Study Completion Date:||April 2010|
|Primary Completion Date:||February 2010 (Final data collection date for primary outcome measure)|
Who met the 2003 Rotterdam criteria.
Mild hyperprolactinaemia group
Who were diagnosed with prolactin levels above the upper limit of normal (24.29 ng/ml) and under 100 ng/ml.
Without PCOS and with normal prolactin levels.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01117272
|Taipei Medical University WanFang Hospital|
|Taipei, Taiwan, 116|
|Principal Investigator:||Ming-I Hsu, MD||Taipei Medical University WanFang Hospital|