An Active Approach to Treat Amblyopia: Perceptual Learning and Video Games
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|ClinicalTrials.gov Identifier: NCT01115283|
Recruitment Status : Recruiting
First Posted : May 4, 2010
Last Update Posted : October 30, 2017
|Condition or disease||Intervention/treatment||Phase|
|Amblyopia||Behavioral: Perceptual learning Behavioral: Video Games Behavioral: Occlusion therapy||Phase 1 Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||50 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||None (Open Label)|
|Official Title:||Improving Spatial and Temporal Vision in Adult and Juvenile Amblyopia|
|Study Start Date :||July 2015|
|Estimated Primary Completion Date :||May 2020|
|Estimated Study Completion Date :||May 2020|
Experimental: Perceptual learning
Patients will be asked to practice a range of visual discrimination tasks for a period of time (each therapy session:1-2 hrs, 4-5 sessions/wk for ~1-6 months).
Behavioral: Perceptual learning
Research participants will be asked to practice a visual discrimination task (e.g. position acuity, contrast sensitivity, stereoacuity etc) in our laboratory for a period of time (2 hrs/day, 5 days/week).
Experimental: Occlusion therapy
The fellow sound will be covered with a standard eye patch for a period of time (1-2 hrs/day, 4-5 days/wk for ~1-3 months). The idea is to push the brain to use the weaker amblyopic eye.
Behavioral: Occlusion therapy
Research participants will be required to cover the good eye during the day in order to push the brain to use the amblyopic eye (2 hrs/day, 5 days/week for 2-4 weeks).
Experimental: Video game
Patients will be asked to play videogames for a period of time (each therapy session:1-2 hrs, 4-5 sessions/wk for ~1-6 months).
Behavioral: Video Games
Research participants will be asked to play "off-the-shelf" video games in our laboratory for a period of time (2 hrs/day, 5 days/week).
- Amblyopic vision [ Time Frame: 9 months ]Improvement in amblyopic vision : visual acuity and stereoacuity
- Spatial vision [ Time Frame: 9 months ]Improvement in spatial vision (eg. contrast sensitivity, positional acuity and spatial attention)
- Temporal vision [ Time Frame: 9 months ]Improvement in temporal processing and temporal vision
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01115283
|Contact: Roger W Li, OD, PhDfirstname.lastname@example.org|
|United States, California|
|Minor Hall 486, School of Optometry, University of California, Berkeley||Recruiting|
|Berkeley, California, United States, 94720|
|Contact: Roger W Li, OD,PhD 510-643-8685 email@example.com|
|Principal Investigator: Roger W Li, OD, PhD|
|Principal Investigator:||Roger W Li, OD, PhD||School of Optometry, Univeristy of california-Berkeley|
|Principal Investigator:||Dennis M Levi, OD, PhD||School of Optometry, Univerisity of California-Berkeley|