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Effects of Water-soluble Olive Extract Supplementation

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ClinicalTrials.gov Identifier: NCT01113827
Recruitment Status : Completed
First Posted : April 30, 2010
Last Update Posted : March 27, 2012
Sponsor:
Collaborator:
DSM Nutritional Products, Inc.
Information provided by (Responsible Party):
University of Texas at Austin

Brief Summary:

Six weeks of supplementation of an olive extract will:

  • Improve antioxidant status
  • Reduce inflammation
  • Reduce muscle damage
  • Improve exercise performance
  • Improve exercise recovery as compared to a placebo.

Condition or disease Intervention/treatment Phase
Healthy Dietary Supplement: Olive Extract Dietary Supplement: Placebo Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 61 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Basic Science
Official Title: Effects of Water-soluble Olive Extract on Antioxidant Status, Exercise Performance, Muscle Metabolism, Muscle Damage and Inflammation
Study Start Date : February 2010
Actual Primary Completion Date : July 2011
Actual Study Completion Date : February 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Antioxidants
U.S. FDA Resources

Arm Intervention/treatment
Active Comparator: 150mg olive extract Dietary Supplement: Olive Extract
Capsule form ingested 1x/day for 6 weeks
Active Comparator: 50mg olive extract Dietary Supplement: Olive Extract
Capsule form ingested 1x/day for 6 weeks
Placebo Comparator: Placebo control Dietary Supplement: Placebo
Placebo



Primary Outcome Measures :
  1. Improved Antioxidant Status [ Time Frame: 6 weeks ]

Secondary Outcome Measures :
  1. Reduced Inflammation [ Time Frame: 6 weeks ]


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Ages Eligible for Study:   20 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Recreational exerciser
  • BMI <= 30
  • Non-smoker

Exclusion Criteria:

  • Blood pressure over 140/90
  • Type I or Type II diabetes
  • Renal, hepatic or cardiac disease
  • Current infectious disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01113827


Locations
United States, Texas
The University of Texas at Austin
Austin, Texas, United States, 78712
Sponsors and Collaborators
University of Texas at Austin
DSM Nutritional Products, Inc.
Investigators
Principal Investigator: John Ivy, Ph.D. The University of Texas at Austin

Responsible Party: University of Texas at Austin
ClinicalTrials.gov Identifier: NCT01113827     History of Changes
Other Study ID Numbers: 2009-09-01-OLIV
First Posted: April 30, 2010    Key Record Dates
Last Update Posted: March 27, 2012
Last Verified: February 2012

Keywords provided by University of Texas at Austin:
Olive
antioxidant
exercise
inflammation
recovery
Healthy men

Additional relevant MeSH terms:
Antioxidants
Molecular Mechanisms of Pharmacological Action
Protective Agents
Physiological Effects of Drugs