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SPECT/CT in the Diagnosis of Dementia (DEMSPET)

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ClinicalTrials.gov Identifier: NCT01112501
Recruitment Status : Completed
First Posted : April 28, 2010
Last Update Posted : April 28, 2010
Sponsor:
Collaborator:
University of Eastern Finland
Information provided by:
Kuopio University Hospital

Brief Summary:
Aim of the study is to evaluate whether Tc-99m-ECD-SPECT/CT enhances early diagnosis of dementia in two specific patient groups: (1) patient with mild cognitive impairment, and (2) patient with possible symptoms and signs of frontotemporal dementia. Evaluation of SPECT/CT data is performed both by visual and quantitative voxel-based analyses (Statistical Parametric Mapping). The final diagnosis is based on up to four years clinical follow-up.

Condition or disease
Dementia

Study Type : Observational
Actual Enrollment : 82 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: SPECT/CT in the Diagnosis of Dementia
Study Start Date : September 2006
Actual Primary Completion Date : January 2010
Actual Study Completion Date : January 2010

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Dementia
U.S. FDA Resources




Primary Outcome Measures :
  1. Final diagnosis [ Time Frame: 4 years ]
    (1) controls, (2) stable mild cognitive impairment (MCI), (3)MCI converted to Alzheimers's disease (AD), (4) frontotemporal dementia (FTD), suspected FTD converted to AD, (5) other final diagnoses



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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Subjects with possible/suspected early dementia
Criteria

Inclusion Criteria (one of these):

  • healthy control
  • mild cognitive impairment (recruited from a population based data)
  • clinically suspected frontotemporal dementia (unset diagnosis)

Exclusion Criteria:

  • unable to be scanned with SPECT/CT

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01112501


Locations
Finland
Kuopio University Hospital
Kuopio, Finland, 70211
Sponsors and Collaborators
Kuopio University Hospital
University of Eastern Finland

Responsible Party: Esko Vanninen / Professor, Kuopio University Hospital
ClinicalTrials.gov Identifier: NCT01112501     History of Changes
Other Study ID Numbers: KUH5031339
First Posted: April 28, 2010    Key Record Dates
Last Update Posted: April 28, 2010
Last Verified: April 2010

Keywords provided by Kuopio University Hospital:
Diagnosis
Dementia
Imaging

Additional relevant MeSH terms:
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders