Effect of Heart Rate on Left Ventricular Performance
Recruitment status was: Recruiting
|Myocardial Function Myocardial Strain||Procedure: Increase in paced heart rate|
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
|Official Title:||Effect of Heart Rate on Left Ventricular Performance|
- Segmental Strain [ Time Frame: approx. 20 minutes ]Segmental Strain by speckle tracking method will be calculated for every stage of each study.
- LV function [ Time Frame: Approx. 20 minutes ]Parameters of systolic and diastolic function will be calculated at each stage.
|Study Start Date:||April 2010|
|Estimated Study Completion Date:||April 2012|
|Estimated Primary Completion Date:||April 2012 (Final data collection date for primary outcome measure)|
Procedure: Increase in paced heart rate
Participants will be patients with pacemakers and normal A-V node conduction with a possibility for right atrial pacing mode.
Detailed Echo studies will be performed at baseline. Echo studies will be repeated at each pacing stage, stages defined as 10 bpm increments in paced heart rate. Each stage will last 2-3 min or as long as it takes to record the echo study. Heart rate will be increased to 85% of predicted heart rate for age or at to appearance of signs of ischemia.
Hemodynamic parameters will be recorded and segmental longitudinal strain will be calculated (as well as other Echo data), for each stage.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01112176
|Contact: David S. Blondheim, MDemail@example.com|
|Contact: David S. Blondheim, MD|
|Hille Yaffe Medical Ceter||Recruiting|
|Hadera, Israel, 38100|
|Contact: David Blondheim, MD 97246304488 firstname.lastname@example.org|
|Principal Investigator: David S. Blondheim, MD|
|Principal Investigator:||David S. Blondheim, MD||Hillel Yaffe Medical Center|