Radiation Dose From Computed Tomography Before and After Implementation of a High Pitch Dual Spiral Technique (FLASH)
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|ClinicalTrials.gov Identifier: NCT01111760|
Recruitment Status : Completed
First Posted : April 28, 2010
Last Update Posted : April 5, 2013
|Condition or disease|
|Atherosclerosis of Coronary Artery Cardiovascular Disease Pulmonary Embolism Aortic Aneurysm Without Mention of Rupture Nos|
Computed tomography has emerged as the "gold standard" for the diagnosis of a broad range of medical diagnoses. For cardiac imaging alone, the installation of CT scanners in US cardiology practices alone has tripled over the past 2 years. Patients who undergo cardiac CTA (computed tomography angiography) may be subjected to relatively high doses of ionizing radiation (ie. 4 times annual background radiation) during the diagnosis and management of coronary artery disease. Current radiation doses for cardiac CT examinations are comparable to the effective doses for patients undergoing nuclear stress tests or cardiac catheterization (ie. approximately 10-15 milliSieverts). In addition, non cardiac CT protocols, such as chest CT examinations for the evaluation of pulmonary arteries, thoracic and abdominal aorta, and lung nodules, are associated with significant radiation exposure. Many patients undergo repeated CT examinations over several years for such pathology. There is a growing public concern regarding the cancer risk associated with such radiation.
Recent major technological advances have been made with the advent of newer generation CT scanners which allow significant radiation dose reduction. One such scanner, the dual source CT, is a new high pitch dual source spiral technique that offers the ability to image a patient's chest with ECG gated imaging protocols within a single second. These technological advances allow significant radiation dose savings, often resulting in effective radiation doses of less than one millisievert (mSv).
|Study Type :||Observational|
|Actual Enrollment :||334 participants|
|Official Title:||Radiation Dose From Computed Tomography Before and After Implementation of a High Pitch Dual Spiral Technique|
|Study Start Date :||May 2010|
|Actual Primary Completion Date :||December 2012|
|Actual Study Completion Date :||February 2013|
- Comparison of the radiation dose for chest CT examinations using current technology with radiation dose exposure using the newest generation CT scanner. [ Time Frame: Time of CT scan ]The primary objective of this study is to compare the estimated radiation dose for chest CT examinations (cardiac and non cardiac) performed using current technology (ie. Retrospective gated CT examinations on the 64 slice and dual source Definition Siemens CT scanners) with the radiation exposure using the newest generation CT scanner (high pitch dual source spiral technique).
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01111760
|United States, Michigan|
|William Beaumont Hospital-Royal Oak|
|Royal Oak, Michigan, United States, 48073|
|Principal Investigator:||Michael Gallagher, MD||William Beaumont Hospitals|
|Study Director:||Gilbert Raff, MD||William Beaumont Hospitals|