Differences in Coagulation Test Kits
The aim of this study is to assess the effect of Innovin® reagent on laboratory results when compared with the Thromborel® S.
Effect of Different Reagents.
Oral Anticoagulant Therapy
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||The Effects of Different Reagents on Coagulation Tests: Innovin Versus Thromborel-S.|
|Study Start Date:||January 2010|
|Study Completion Date:||March 2010|
|Primary Completion Date:||March 2010 (Final data collection date for primary outcome measure)|
Patients receiving and not receiving oral anticoagulant therapy.
Group I: Patients not receiving OAT, Group II: Patients under OAT and INR values in good therapeutic range and Group III: Patients under OAT and INR values over the therapeutic range.
Thromboplastins are the screening tests which are used in the diagnosis of acquired or inherited disorders of the coagulation system but still, alterations between various thromboplastin preparations in the measurements remains a problem.Blood samples are going to drawn from patients receiving and not receiving oral anticoagulant therapy (OAT) during their routine laboratory tests. Samples are subjected to analysis by using Thromborel® S and Innovin® reagents. Mean International Normalized Ratio (INR), prothrombin time and fibrinogen values are going to compared. To further study the importance of this phenomenon the cohort will be divided into three subgroups according to the INR values as Group I: Patients not receiving OAT, Group II: Patients under OAT and INR values in good therapeutic range and Group III: Patients under OAT and INR values over the therapeutic range.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01109667
|Turkiye Yuksek Ihtisas Hospital|
|Ankara, Turkey, 06100|