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Prevention of Stroke and Dementia in Primary Care (INVADE)

This study has been terminated.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01107548
First Posted: April 21, 2010
Last Update Posted: February 20, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborators:
Allgemeine Ortskrankenkasse Bayern (AOK)
Stiftung Deutsche Schlaganfall-Hilfe
Ratiopharm GmbH
Sanofi-Synthelabo
Organon
Teva Pharma GmbH
Bayer
Berlin-Chemie Menarini
Information provided by:
Technische Universität München
  Purpose

In Western Countries, stroke and dementia are the main causes of long-term disability, dependency, and nursing home admission. Due to demographic trends a continuous increase of patient numbers can be expected.

There is growing evidence that vascular risk factors which are implicated in the etiology of stroke also play important etiologic roles in both vascular dementia and Alzheimer disease. The present project is aimed at the reduction of stroke and dementia by means of a systematic detection and subsequent treatment of vascular risk factors by the family doctor based on established guidelines.


Condition Intervention
Stroke Dementia Disability Other: Systematic detection of vascular risk factors and subsequent evidence-based treatment

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Intervention Project of Cerebrovascular Diseases and Dementia in the District of Ebersberg

Resource links provided by NLM:


Further study details as provided by Technische Universität München:

Primary Outcome Measures:
  • Incidence of long-term care disability [ Time Frame: 8 years ]
  • Incidence of stroke [ Time Frame: 8 Years ]

Secondary Outcome Measures:
  • Reduction of cardiovascular risk factors [ Time Frame: 8 years ]

Enrollment: 3908
Study Start Date: January 2001
Study Completion Date: March 2010
Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Evidence-based treatment, lifestyle counseling Other: Systematic detection of vascular risk factors and subsequent evidence-based treatment

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   55 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Age 55 years or over
  • Member of a particular health insurance plan (AOK)
  • Resident of the district of Ebersberg

Exclusion Criteria:

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01107548


Locations
Germany
Depts. of Psychiatry and Neurology, Technische Universität München
Munich, Germany, D-81675
Sponsors and Collaborators
Technische Universität München
Allgemeine Ortskrankenkasse Bayern (AOK)
Stiftung Deutsche Schlaganfall-Hilfe
Ratiopharm GmbH
Sanofi-Synthelabo
Organon
Teva Pharma GmbH
Bayer
Berlin-Chemie Menarini
Investigators
Principal Investigator: Horst Bickel, PhD Dept. of Psychiatry, Technical University of Munich
  More Information

Additional Information:
Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Horst Bickel, Dept. of Psychiatry, Technical University of munich
ClinicalTrials.gov Identifier: NCT01107548     History of Changes
Other Study ID Numbers: 080250hb
First Submitted: April 19, 2010
First Posted: April 21, 2010
Last Update Posted: February 20, 2012
Last Verified: April 2010

Additional relevant MeSH terms:
Stroke
Dementia
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Neurocognitive Disorders
Mental Disorders