Beneficial Effects of Pulmonary Rehabilitation for Idiopathic Pulmonary Fibrosis
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ClinicalTrials.gov Identifier: NCT01107028 |
Recruitment Status
:
Completed
First Posted
: April 20, 2010
Last Update Posted
: March 29, 2017
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Condition or disease | Intervention/treatment |
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Idiopathic Pulmonary Fibrosis | Other: Standard pulmonary rehabilitation program |
Subjects will come to our center to be enrolled. Baseline data collection (performance of a six-minute walk test and completion of questionnaires) and randomization to one of two groups--either Rehab or Wait--will take place at the same enrollment visit if time permits. Subjects in either group will complete pulmonary rehabilitation, just at slightly different times, depending on which group they are randomized to.
Pulmonary rehabilitation is a program run by respiratory and/or physical therapists and other health professionals that involves exercise, education, and support with the goals to improve functional capacity, symptom management, and well-being. It will last 6-8 weeks, during which time, subjects will complete 18 approximately hour-long sessions. Pulmonary rehabilitation may be completed at any local center that makes travel convenient.
Data collection visits will take place at National Jewish Health at baseline, eight weeks (without intervening pulmonary rehabilitation in the Wait group), after completion of pulmonary rehabilitation (time varies, depending on the randomization group), and finally six months after completion of the pulmonary rehabilitation program.
Study Type : | Observational |
Actual Enrollment : | 41 participants |
Observational Model: | Case-Only |
Time Perspective: | Prospective |
Official Title: | Pulmonary Rehabilitation for Idiopathic Pulmonary Fibrosis |
Study Start Date : | February 2010 |
Actual Primary Completion Date : | October 2014 |
Actual Study Completion Date : | October 2014 |

Group/Cohort | Intervention/treatment |
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Rehab
Subjects randomized to the Rehab group will have data collected at baseline and then within one week enroll in a pulmonary rehabilitation program. Data will again be collected within one week of completing pulmonary rehabilitation and again six months later.
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Other: Standard pulmonary rehabilitation program
At the assigned time, subjects will complete a six-week, outpatient pulmonary rehabilitation program at any local center that has such a program.
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Wait
Subjects randomized to the Wait group will have data collected at baseline and wait eight weeks before enrolling in a pulmonary rehabilitation program. Data will again be collected within one week of completing pulmonary rehabilitation and again six months later.
|
Other: Standard pulmonary rehabilitation program
At the assigned time, subjects will complete a six-week, outpatient pulmonary rehabilitation program at any local center that has such a program.
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- Six-minute walk distance [ Time Frame: Eight weeks ]Distance walked during a standard six-minute walk test.
- dyspnea, fatigue, anxiety, depression, quality of life [ Time Frame: Eight weeks ]
- Six minute walk distance [ Time Frame: Six months after completion of pulmonary rehabilitation ]
- dyspnea, fatigue, anxiety, depression, quality of life [ Time Frame: Six months after completion of pulmonary rehabilitation ]

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Ages Eligible for Study: | 40 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
Inclusion Criteria:
- Age > 40 years
- IPF
- Able to walk unassisted for balance
- Able to speak and understand English well enough to complete complex tasks with directions given in English
Exclusion Criteria:
- Pulmonary fibrosis not due to IPF
- Coexisting comorbid conditions that would make exercise contraindicated

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01107028
United States, Colorado | |
National Jewish Health | |
Denver, Colorado, United States, 80206 |
Principal Investigator: | Jeffrey J. Swigris, DO, MS | National Jewish Health |
Additional Information:
Publications:
Responsible Party: | Jennifer Brandorff, Regulatory Manager, National Jewish Health |
ClinicalTrials.gov Identifier: | NCT01107028 History of Changes |
Other Study ID Numbers: |
NJ230 K23HL092227-01A2 ( U.S. NIH Grant/Contract ) |
First Posted: | April 20, 2010 Key Record Dates |
Last Update Posted: | March 29, 2017 |
Last Verified: | March 2017 |
Keywords provided by Jennifer Brandorff, National Jewish Health:
Idiopathic pulmonary fibrosis Dyspnea Functional capacity Quality of life |
Additional relevant MeSH terms:
Fibrosis Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis Idiopathic Interstitial Pneumonias |
Pathologic Processes Lung Diseases Respiratory Tract Diseases Lung Diseases, Interstitial |