Associations Between Diabetes, Arterial Stiffness and Fibulin-1 in Patients Undergoing Heart- and Vascular Surgery?
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|ClinicalTrials.gov Identifier: NCT01106573|
Recruitment Status : Unknown
Verified April 2010 by Odense University Hospital.
Recruitment status was: Not yet recruiting
First Posted : April 20, 2010
Last Update Posted : April 20, 2010
Diabetes Mellitus (DM) is frequently appearing in patients with cardiovascular disease and these patients, as a consequence herby, has a lesser prognosis. DM is often related to increased arterial stiffness and hypertension. The investigators thesis is that DM and pre-diabetes is prevalent in patients undergoing cardiovascular surgery and to some extend is under-diagnosed. At the same time the investigators imagine that DM is closely related to the degree of arterial stiffness, and that these parameters are closely related to a new biochemical marker, fibulin-1.
The investigators aim to describe the prevalence of type 2 DM and dysmetabolism in patients admitted to the hospital to undergo cardiovascular surgery and besides that to investigate if there is a connection between the degree of the dysmetabolism and arterial disease, by studying arterial stiffness and by measuring a new biochemical marker, fibulin-1, which the investigators newly have identified. The results of this project will give us a measure for the quantity of unknown DM in patients undergoing cardiovascular surgery and furthermore tell us more in terms of the connections between a newly identified plasma arterial marker, arterial stiffness and diabetes.
|Condition or disease|
|Coronary Artery Disease Arteriosclerosis Carotid Stenosis Thrombosis Aortic Aneurysm, Abdominal|
|Study Type :||Observational|
|Estimated Enrollment :||1400 participants|
|Official Title:||Is There an Association Between the Presence of Diabetes, the Degree of Arterial Stiffness and a New Plasma Marker for Vascular Elasticity, Fibulin-1 in Patients Undergoing Heart- and Vascular Surgery?|
|Study Start Date :||June 2010|
|Estimated Primary Completion Date :||May 2013|
|Estimated Study Completion Date :||May 2013|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01106573
|Contact: Maria Lyck Hansen, Ph.d email@example.com|
|Contact: Lars Melholt Rasmussen, Professor, MD||0045-6541 firstname.lastname@example.org|
|Department of Biochemnistry and Farmacology, Odense University Hospital||Not yet recruiting|
|Odense, Denmark, 5000|
|Principal Investigator: Maria Lyck Hansen, Ph.d student|
|Study Chair:||Lars Melholt Rasmussen, Professor, MD||Department of Biochemnistry and Farmacology, Odense University Hospital|