COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Cholecyst- Versus Cystic Duct Cholangiography During Laparoscopic Cholecystectomy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01103570
Recruitment Status : Completed
First Posted : April 14, 2010
Last Update Posted : April 14, 2010
Information provided by:
Theodor Bilharz Research Institute

Brief Summary:
Standard cystic duct cholangiography (CDC) during laparoscopic cholecystectomy can be difficult, time consuming and bile duct injury may be caused by attempts to cannulate the cystic duct. Operative cholangiography performed by direct puncture of the gall bladder fundus or Cholecystocholangiography (CCC) is a valid and easier alternative.

Condition or disease Intervention/treatment Phase
Laparoscopic Cholecystectomy Gall Stone Disease Biliary Tract Anatomy Common Bile Duct Stones. Procedure: cholecystocholangiography Procedure: cystic duct cholangiography Phase 4

Detailed Description:
This study was conducted on 60 patients with symptomatic gall bladder stones undergoing laparoscopic cholecystectomy. Patients were randomized into two groups: Group (1) was evaluated by cholecyst-cholangiography by puncture through the gall bladder fundus. Group (2) was evaluated for the standard cystic duct cholangiography.Cholangiography was considered successful if it could be performed with complete delineation of the biliary tree with flow of the dye through the duodenum occurred. It is to be noted that inability to cannulate the cystic duct for example, is considered a failure.

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Cholecystocholangiography Versus Cystic Duct Cholangiography During Laparoscopic Cholecystectomy: A Prospective Controlled Randomized Trial
Study Start Date : March 2009
Actual Primary Completion Date : January 2010
Actual Study Completion Date : March 2010

Arm Intervention/treatment
Experimental: group 1 cholecystocholangiography
cholangiography via gall bladder
Procedure: cholecystocholangiography
a central venous pressure catheter was introduced through the anterior abdominal wall subcostally in a direction parallel to the gallbladder bed under direct vision so that it emerges close to the gall bladder. Then the catheter was advanced into the fundus of the gall bladder . The dye was prepared by diluting 20ml of 76% urografin with 20ml normal saline in a 50ml syringe
Other Name: cholangiography via gallbladder

Experimental: group2 cystic duct cholangiography
cystic duct cholangiography
Procedure: cystic duct cholangiography
Then a 14G cannula was introduced through the anterior abdominal wall subcostally, (size 4F), was introduced through this cannula. The catheter was inserted into the cystic duct no more than 1 cm, by a grasper Then a 50ml syringe with the diluted urografin dye, as above, was attached to the catheter and cholangiography was performed by slowly injecting the dye under control of C-arm image intensifier.
Other Name: cholangiography via cystic dict

Primary Outcome Measures :
  1. success rate [ Time Frame: 6 months ]

Secondary Outcome Measures :
  1. procedure-related complications [ Time Frame: 3 months ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years to 55 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • patients with symptomatic gall bladder stones.

Exclusion Criteria:

  • unfit Patients and/or had previous surgery
  • history of obstructive jaundice and acute attacks or previous ERCP were excluded

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01103570

Layout table for location information
Department of General Surgery * Theodore Bilharz Research Institute
Cairo, Egypt, 112124
Sponsors and Collaborators
Theodor Bilharz Research Institute
Layout table for additonal information
Responsible Party: magdy elsebae, Department of General Surgery * Theodore Bilharz Research Institute Identifier: NCT01103570    
Other Study ID Numbers: cholangiography
First Posted: April 14, 2010    Key Record Dates
Last Update Posted: April 14, 2010
Last Verified: April 2010
Keywords provided by Theodor Bilharz Research Institute:
Laparoscopic cholecystectomy
Intra-operative cholangiography
Additional relevant MeSH terms:
Layout table for MeSH terms
Pathological Conditions, Anatomical
Biliary Tract Diseases
Digestive System Diseases
Gallbladder Diseases