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Prophylactic Selective Lateral Neck Dissection in Patients With Papillary Thyroid Carcinoma

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01103557
First Posted: April 14, 2010
Last Update Posted: April 14, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Pusan National University Hospital
  Purpose
The purpose of this study is to prospectively analyze the incidence of occult lateral neck metastasis (LNM) and to elucidate the factors that predict LNM in papillary thyroid carcinoma (PTC) with central neck metastasis (CNM) by performing prophylactic selective lateral neck dissection (SND).

Condition Intervention
Thyroid Neoplasm Lymphatic Metastasis Procedure: prophylactic selective lateral neck dissection

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: The Effectiveness of Prophylactic Selective Lateral Neck Dissection in Papillary Thyroid Carcinoma Patients With Central Neck Metastasis

Resource links provided by NLM:


Further study details as provided by Pusan National University Hospital:

Enrollment: 62
Intervention Details:
    Procedure: prophylactic selective lateral neck dissection
    Level II, III, IV lymph node dissection
Detailed Description:
The lymphatic drainage pattern of the thyroid is uniform and consistent, and therefore, metastatic patterns are relatively predictable. Initial nodal metastasis in PTC usually occurs in the paratracheal and pretracheal nodes in level VI of the central compartment of the ipsilateral neck and spreads to the lateral cervical lymph nodes. Macroscopic skip metastases to the lateral compartment of the neck in the absence of central disease are uncommon.
  Eligibility

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Ages Eligible for Study:   20 Years to 76 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Papillary thyroid carcinoma with central neck metastasis
  • No evidence of lateral neck metastasis as determined by high-resolution neck ultrasonography and computed tomography

Exclusion Criteria:

  • History of previous thyroid operation
  • Isthmic thyroid lesion
  Contacts and Locations
No Contacts or Locations Provided
  More Information

Responsible Party: Yun-Sung Lim, Pusan National University Hospital
ClinicalTrials.gov Identifier: NCT01103557     History of Changes
Other Study ID Numbers: PTC_CND_LND
First Submitted: April 12, 2010
First Posted: April 14, 2010
Last Update Posted: April 14, 2010
Last Verified: January 2010

Keywords provided by Pusan National University Hospital:
Papillary thyroid carcinoma with neck metastasis
neck dissection

Additional relevant MeSH terms:
Carcinoma
Neoplasm Metastasis
Thyroid Diseases
Thyroid Neoplasms
Lymphatic Metastasis
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Neoplastic Processes
Pathologic Processes
Endocrine System Diseases
Endocrine Gland Neoplasms
Neoplasms by Site
Head and Neck Neoplasms