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Maintenance of Vitamin D Level by UVB Radiation

This study has been completed.
The Danish Medical Research Council
Information provided by:
Bispebjerg Hospital Identifier:
First received: April 8, 2010
Last updated: NA
Last verified: April 2010
History: No changes posted
The purpose of the study is to determine the frequency of UVB radiations necessary to maintain the Vitamin D level during winter time.

Condition Intervention
Vitamin D Status
Radiation: Broadband UVB
Other: Control group

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Participant, Investigator)
Primary Purpose: Basic Science
Official Title: How Much UVB Radiation is Necessary to Maintain Summer Vitamin D Level During Winter?

Resource links provided by NLM:

Further study details as provided by Bispebjerg Hospital:

Primary Outcome Measures:
  • Vitamin D (nmol/l) [ Time Frame: Monthly during 4 months ]
    Vitamin D measured in a blood sample to define the relationship between frequency of UVB radiations and the Vitamin D level.

Secondary Outcome Measures:
  • Parathyroideahormone (pmol/l) [ Time Frame: 4 months ]
    To investigate whether parathyroideahormone is influenced by the UVB radiations.

Enrollment: 75
Study Start Date: October 2008
Study Completion Date: April 2010
Primary Completion Date: March 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Group 1
Body surface area: 88 %
Radiation: Broadband UVB
UVB dose: 1 SED every week
Active Comparator: Group 2
Body surface area: 22 %
Radiation: Broadband UVB
UVB dose: 4 SED every second week
Active Comparator: Group 3
Body surface area: 88 %
Radiation: Broadband UVB
UVB dose: 1 SED every second week
Active Comparator: Group 4
Body surface area: 88 %
Radiation: Broadband UVB
UVB dose: 1 SED every month
No Intervention: Group 5
Body surface area: 0 %
Other: Control group
No intervention

Detailed Description:
The work is addressing vitamin D production after UVB exposure and explore how much UVB radiation which is necessary to maintain a sufficient vitamin D level during the winter period in Denmark. 4 different UVB exposure times and 2 different UVB doses to 2 different body surface areas.

Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • 18-65 years
  • Healthy

Exclusion Criteria:

  • Sun bed use
  • Holiday or business travel south of 45 degrees latitude during trial
  • Illness
  • Drug addiction
  • Pregnancy
  • Lactating
  Contacts and Locations
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Please refer to this study by its identifier: NCT01101243

Bispebjerg Hospital
Copenhagen, NV, Denmark, 2400
Sponsors and Collaborators
Bispebjerg Hospital
The Danish Medical Research Council
Study Chair: Hans Christian Wulf, Professor Bispebjerg Hospital, Department of Dermatology
  More Information

Responsible Party: Morten Bogh MD, Bispebjerg Hospital, Department of Dermatology Identifier: NCT01101243     History of Changes
Other Study ID Numbers: H-C-2008-072
Study First Received: April 8, 2010
Last Updated: April 8, 2010

Keywords provided by Bispebjerg Hospital:
Vitamin D
Body surface area

Additional relevant MeSH terms:
Vitamin D
Growth Substances
Physiological Effects of Drugs
Bone Density Conservation Agents processed this record on May 22, 2017