Low Grade Inflammation in Type 1 Diabetes Children (Coccinelle)
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|ClinicalTrials.gov Identifier: NCT01099956|
Recruitment Status : Completed
First Posted : April 8, 2010
Last Update Posted : October 25, 2011
|Condition or disease|
|Type 1 Diabetes Inflammation|
The increase of type 1 diabetes incidence, particularly in young children leads to conduce new diagnostic and therapeutic strategies, notably for associated chronic morbidity.Measurement of chronic inflammation, with modification of the balance between pro-inflammatory cytokines and anti-inflammatory cytokines, could lead to detect patients with high risk to diabetes chronic morbidity.
After parental consent, blood sampling will be carried out by micromethod for cytokine (500 µl) and CRPhs dosages and glycemia (100 µl) and glycated hemoglobin (1 µl). Urine will be collected (50 ml) in the morning for further researches.
|Study Type :||Observational|
|Actual Enrollment :||80 participants|
|Observational Model:||Case Control|
|Official Title:||Low Grade Inflammation in Type 1 Diabetes Children|
|Study Start Date :||April 2010|
|Actual Primary Completion Date :||July 2010|
|Actual Study Completion Date :||July 2010|
- Increase of Interleukine 6 in group DTI versus control group [ Time Frame: Once at inclusion ]
- Increase of others cytokines (IL1-beta, l'IL-4, l'IL-10 and TNF alpha) and increase of High sensitivity CRP in group DTI versus control group [ Time Frame: Once at inclusion ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01099956
|Children Hospital, Endocrinology Unit|
|Bordeaux, France, 33076|
|Principal Investigator:||Pascal BARAT, MD||University Hospital, Bordeaux, France|