Relationship Between Respiratory Functional Tests and Image Thoracic Techniques in Patients With Neuromuscular Diseases
|ClinicalTrials.gov Identifier: NCT01090674|
Recruitment Status : Completed
First Posted : March 22, 2010
Last Update Posted : February 24, 2014
|Condition or disease||Intervention/treatment|
|Amyotrophic Lateral Sclerosis||Other: No intervention|
|Study Type :||Observational|
|Actual Enrollment :||5 participants|
|Official Title:||Relationship Between Respiratory Functional Tests and Image Thoracic Techniques in Patients With Neuromuscular Diseases.|
|Study Start Date :||June 2007|
|Actual Primary Completion Date :||July 2013|
|Actual Study Completion Date :||July 2013|
U.S. FDA Resources
Patients with amyotrophic lateral sclerosis.
Other: No intervention
We perform in all patients respiratory functional tests, thoracic x-ray, SNIF test and diaphragmatic magnetic resonance imaging.
- Different measures of diaphragmatic mobility, force and function. [ Time Frame: One year ]To compare and correlate all different image techniques that evaluate diaphragmatic mobility with all different respiratory functional variables that measure diaphragmatic (and muscular in general) force and function.
- Diaphragmatic MRI usefulness [ Time Frame: One year ]
- To evaluate dMRI usefulness in monitoring diaphragmatic mobility.
- To evaluate if we can establish a value of diaphragm mobility (in mm) observed with dMRI to suggest the initiation of non invasive ventilation treatment.
- To evaluate if dMRI can predict ALS prognosis.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01090674
|Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau|
|Barcelona, Spain, 08025|