Effect of Colostrum on Gut Permeability and Endotoxin Level in Chronic Alcoholic Disease
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|ClinicalTrials.gov Identifier: NCT01088087|
Recruitment Status : Unknown
Verified November 2009 by Gangnam Severance Hospital.
Recruitment status was: Recruiting
First Posted : March 17, 2010
Last Update Posted : March 17, 2010
Chronic alcohol ingestion is related with leaky gut syndrome. Colostrum is well-studied that it has a effect of decreasing the degree of leaky gut syndrome.
So the investigators are planning to find out whether Colostrum has a effect of decreasing the degree of leaky gut syndrome.
|Condition or disease||Intervention/treatment||Phase|
|Leaky Gut Syndrome||Dietary Supplement: colostrum||Phase 2 Phase 3|
We randomly sort the participant as placebo group and colostrum group. Each group consists of 17 people. and the duration of our study for one participant is 3 weeks. (Participant takes colostrum for 3 weeks.)
When a person gets leaky gut syndrome, his or her endotoxin and lactulose/mannitol ratio (L/M ratio, in urine) can elevate.
So We will compare the value of those two parameters and LFT. etc. after the administration of colostrum or placebo.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||34 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Effect of Colostrum Administration on Improving Gut Permeability and Serum Endotoxin Level in Chronic Alcohol Drinkers With Hepatic Dysfunction|
|Study Start Date :||March 2010|
|Estimated Primary Completion Date :||September 2010|
|Estimated Study Completion Date :||December 2010|
|Placebo Comparator: Colostrum||
Dietary Supplement: colostrum
colostrum, 2g, 2 times a day, for 3 weeks
Other Name: Mucoba
|No Intervention: Sugar pill|
- endotoxin [ Time Frame: 1st visit and 3 weeks after 1st visit ]
- lactulose/mannitol ratio [ Time Frame: 3 weeks ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01088087
|Contact: Jae Yong Shim, Masteremail@example.com|
|Contact: Hong Bae Kim, Bachelor||82-02-584-2823|
|Korea, Republic of|
|Gangnam Severance Hospital : Family medicine department||Recruiting|
|Seoul, Korea, Republic of|
|Contact: Jae Yong Shim, Master 82-02-2019-3155 firstname.lastname@example.org|
|Contact: Hong Bae Kim, Bachelor 82-02-584-2823|
|Sub-Investigator: Hong Bae Kim, Bacholer|
|Study Director:||Jae Yong Shim, Master||Gangnam Severance Hospital|