Education Intervention to Reduce Helminth Infections and Absenteeism in Grade 5 School-children

This study has been completed.
Information provided by:
McGill University Health Center Identifier:
First received: March 10, 2010
Last updated: March 15, 2011
Last verified: March 2011
To efficiently control soil-transmitted helminths (Ascaris, Trichuris, and hookworm), WHO, PAHO, and others recommend the inclusion of an education strategy in school-based deworming programs. However, the effectiveness of such a strategy on the rate of STH re-infection and on education indicators, such as absenteeism, remains to be fully understood. The proposed research aims to evaluate the effectiveness of a post-deworming education intervention targeted to Grade 5 school children enrolled in Belén's schools using a cluster-randomized trial design. Results will be used to inform school-based deworming programs in Peru and other similar endemic areas in Latin America and, indeed, around the world.

Condition Intervention
Behavioral: Health Education Intervention

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: Effectiveness of a Post-deworming Education Intervention to Reduce Soil-transmitted Helminth Infections and Absenteeism in Grade 5 School-children in a Community of Extreme Poverty, Peruvian Amazon

Resource links provided by NLM:

Further study details as provided by McGill University Health Center:

Primary Outcome Measures:
  • Soil-transmitted helminth re-infection (Ascaris, Trichuris, or Hookworm). [ Time Frame: 4 months post-deworming ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Absenteeism rate. [ Time Frame: During the first 4 months following deworming ] [ Designated as safety issue: No ]
  • Eggs per grams reduction rate. [ Time Frame: 4 months post-deworming ] [ Designated as safety issue: No ]
  • Weight gain (kg) [ Time Frame: 4 months post-deworming ] [ Designated as safety issue: No ]
  • Height gain (cm) [ Time Frame: 4 months post-deworming ] [ Designated as safety issue: No ]

Estimated Enrollment: 1101
Study Start Date: April 2010
Study Completion Date: October 2010
Primary Completion Date: October 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Health Education Intervention
Groups of schools receiving the health education intervention
Behavioral: Health Education Intervention
This is a health hygiene education strategy which encourages the pro-active role of both teachers and students and changes in attitudes and practices with the aim of keeping the level of parasite infection low, through increased knowledge.
No Intervention: Control Schools - Regular curriculum
Groups of schools not receiving the health education intervention


Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Girls and boys enrolled in Grade 5 in eligible schools located in the Belén district of Iquitos, Peru. Eligible schools have a minimum of 10 boys and 10 girls enrolled in grade 5.
  • Informed written consent obtained from the parents or legal guardian of the child.
  • Verbal assent from child.

Exclusion Criteria:

  • Parents (or guardians) refusing participation of their child.
  • Child who refuses to participate.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01085799

Asociación Civil Selva Amazónica
Iquitos, Loreto, Peru
Sponsors and Collaborators
McGill University Health Center
Principal Investigator: Theresa W. Gyorkos, PhD McGill University Health Center
Study Director: Martín Casapía, MD, MPH Asociación Civil Selva Amazónica
  More Information

Responsible Party: Theresa W. Gyorkos, PhD, McGill University Identifier: NCT01085799     History of Changes
Other Study ID Numbers: GEN-09-214  HOA-80064 
Study First Received: March 10, 2010
Last Updated: March 15, 2011
Health Authority: Canada: Ethics Review Committee
Peru: Ethics Committee

Keywords provided by McGill University Health Center:
Educational activities
Cluster-randomized controlled trial
School-age children
Ascaris lumbricoides
Trichuris trichiura
STH infections
Intestinal helminth infections

Additional relevant MeSH terms:
Communicable Diseases
Parasitic Diseases processed this record on May 26, 2016