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Vitamin D Zinc Fever

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified March 2010 by Assaf-Harofeh Medical Center.
Recruitment status was:  Not yet recruiting
Sponsor:
Information provided by:
Assaf-Harofeh Medical Center
ClinicalTrials.gov Identifier:
NCT01080950
First received: March 3, 2010
Last updated: March 4, 2010
Last verified: March 2010
  Purpose

Zinc and vitamin d deficiency are associated with a state of inflammation/atherosclerosis.

There are studies demonstrating an association between vitamin d deficiency and respiratory illnesses.

Both zinc and vitamin d are associated with oxidative stress and inflammation.


Condition
Sepsis
Fever
Vitamin D

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Vitamin d and Zinc Levels in Patients With Fever

Resource links provided by NLM:


Further study details as provided by Assaf-Harofeh Medical Center:

Biospecimen Retention:   Samples Without DNA
blood drawn for vitamin d will be freezed and stored until all samples have been collected and only than will it be analyzed.

Estimated Enrollment: 200
Study Start Date: March 2010
Estimated Study Completion Date: March 2011
Estimated Primary Completion Date: March 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
fever zinc vit. d
patients with fever but without sepsis
sepsis zinc vit. d
patients with sepsis

Detailed Description:

Both vit. d and zinc share anti inflammatory and anti oxidative actions. vit. d deficiency is associated with an increase in serum levels of proinflammatory cytokines and decreased levels of anti inflammatory cytokines.

there are reports concerning the association of vit. d deficiency with infections.

  Eligibility

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
patients hospitalized with fever and or sepsis.
Criteria

Inclusion Criteria:

  • age>18 years

Exclusion Criteria:

  • CCT<90
  • taking calcium
  • hyper/hypoparathyroidism
  • active malignancy.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01080950

Locations
Israel
Assaf Harofeh Mc
Zerifin, Israel
Sponsors and Collaborators
Assaf-Harofeh Medical Center
  More Information

Responsible Party: renana shor md, Assaf - Harofeh MC
ClinicalTrials.gov Identifier: NCT01080950     History of Changes
Other Study ID Numbers: vitamin d zinc and fever 
Study First Received: March 3, 2010
Last Updated: March 4, 2010
Health Authority: Israel: Ministry of Health

Keywords provided by Assaf-Harofeh Medical Center:
zinc
sepsis
fever
vitamin d

Additional relevant MeSH terms:
Sepsis
Fever
Infection
Systemic Inflammatory Response Syndrome
Inflammation
Pathologic Processes
Body Temperature Changes
Signs and Symptoms
Vitamins
Vitamin D
Ergocalciferols
Zinc
Micronutrients
Growth Substances
Physiological Effects of Drugs
Bone Density Conservation Agents
Trace Elements

ClinicalTrials.gov processed this record on December 07, 2016