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Coffee Trial - Does Coffee Intake Reduce Postoperative Ileus After Elective Colectomy?

This study has been completed.
Information provided by (Responsible Party):
Nuh Rahbari, University of Heidelberg Identifier:
First received: March 1, 2010
Last updated: September 29, 2011
Last verified: September 2011
The purpose of the investigators study is to investigate the effects of coffee on the return of bowel function and appetite, length of hospital stay, and complications after elective open colectomy in a prospective randomized trial. The primary efficacy endpoint is time to first bowel movement.

Condition Intervention
Other: Postoperative coffee
Other: water

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Supportive Care
Official Title: Does Coffee Intake Reduce Postoperative Ileus After Elective Colectomy?

Resource links provided by NLM:

Further study details as provided by Nuh Rahbari, University of Heidelberg:

Primary Outcome Measures:
  • Time to first bowel movement [ Time Frame: patients postoperative in hospital stay (mean 6 days) ]
    Time from end of surgery until patient's first bowel movement (i.e. passage of stool).

Enrollment: 80
Study Start Date: March 2010
Study Completion Date: March 2011
Primary Completion Date: March 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Treatment arm: coffee
coffee administration
Other: Postoperative coffee

schedule for coffee administration for the present trial was chosen as follows (starting 6 hours postoperatively):

  • 08:00 100mL beverage
  • 12:00 100mL beverage
  • 16:00 100mL beverage
Other Name: Lavazza Blue Espresso Dolce 100% Arabica coffee
Placebo Comparator: Water arm
The control drink consists of 100 ml warm water
Other: water

The control drink consists of 100 ml warm water which is administered according a same fixed schedule as Group A starting 6 hours postoperatively:

  • 08:00 100mL beverage
  • 12:00 100mL beverage
  • 16:00 100mL beverage
Other Name: tap water

Detailed Description:
Coffee is a popular beverage. Its effects on general well being, central nervous system and cardiovascular system are well known, but there is limited information regarding its effects on gastrointestinal function.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients scheduled for elective open or laparoscopic colectomy
  • Age equal or greater than 18 years
  • Informed consent

Exclusion Criteria:

  • Participation in concurrent intervention trials
  • Need for a stoma
  • Known hypersensitivity or allergy to coffee
  • Expected lack of compliance
  • Impaired mental state or language problems
  • change in surgical procedure
  Contacts and Locations
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Please refer to this study by its identifier: NCT01079442

Salem Krankenhaus
Heidelberg, Germany, 69120
University hospital
Heidelberg, Germany, 69120
Kreiskrankenhaus GRN Sinsheim
Sinsheim, Germany
Sponsors and Collaborators
Heidelberg University
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Nuh Rahbari, chief resident, University of Heidelberg Identifier: NCT01079442     History of Changes
Other Study ID Numbers: NNR-6
Study First Received: March 1, 2010
Last Updated: September 29, 2011

Keywords provided by Nuh Rahbari, University of Heidelberg:
postoperative ileus after colonic resections processed this record on May 25, 2017