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Salivary Proteome and Sensitivity to Bitterness (PROTAMER)

This study has been completed.
Information provided by:
Institut National de la Recherche Agronomique Identifier:
First received: March 2, 2010
Last updated: NA
Last verified: February 2010
History: No changes posted
This study aims to establish whether the protein composition of healthy males contribute to their sensitivity to the bitterness of caffeine.

Condition Intervention
Other: caffeine

Study Type: Interventional
Study Design: Primary Purpose: Basic Science

Resource links provided by NLM:

Further study details as provided by Institut National de la Recherche Agronomique:

Arms Assigned Interventions
Experimental: caffeine Other: caffeine


Ages Eligible for Study:   25 Years to 45 Years   (Adult)
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • healthy volunteers

Exclusion Criteria:

  • smokers
  • currently suffering from oral pathologies
  • sensory aversion to bitterness
  Contacts and Locations
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Please refer to this study by its identifier: NCT01079338

Sponsors and Collaborators
Institut National de la Recherche Agronomique
Principal Investigator: Martine Morzel, PhD Institut National de la Recherche Agronomique
  More Information Identifier: NCT01079338     History of Changes
Other Study ID Numbers: AFSSAPS-2009-A00320-57 
Study First Received: March 2, 2010
Last Updated: March 2, 2010
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Keywords provided by Institut National de la Recherche Agronomique:
sensitivity to caffeine

Additional relevant MeSH terms:
Central Nervous System Stimulants
Physiological Effects of Drugs
Phosphodiesterase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Purinergic P1 Receptor Antagonists
Purinergic Antagonists
Purinergic Agents
Neurotransmitter Agents processed this record on October 21, 2016