Prevalence of Intracranial Aneurysm in Hong Kong Chinese

This study has been completed.
Information provided by (Responsible Party):
George KC Wong, Chinese University of Hong Kong Identifier:
First received: February 26, 2010
Last updated: April 22, 2013
Last verified: April 2013
Intracranial aneurysm (localized dilatation in weakened blood vessel wall) rupture is a catastrophic disease, with half of the victims died and many of the survivors disabled. There is currently no data in the literature for the Chinese population concerning the prevalence, characteristics (location and size) and risk of harboring an unruptured intracranial aneurysm. In this study, the investigators aim to study the population prevalence and characteristics (location and size) of intracranial aneurysm in Hong Kong Chinese, and its cost-effectiveness. The screening is carried out using magnetic resonance angiography (MRA), with a 3-T magnetic resonance system, which is a well-established non-invasive method for intracranial aneurysm detection.

Intracranial Aneurysm

Study Type: Observational
Study Design: Observational Model: Ecologic or Community
Time Perspective: Prospective
Official Title: Prevalence of Intracranial Aneurysm in Hong Kong Chinese

Resource links provided by NLM:

Further study details as provided by Chinese University of Hong Kong:

Primary Outcome Measures:
  • Intracranial aneurysm [ Time Frame: Three years ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Other intracranial pathologies [ Time Frame: Three years ] [ Designated as safety issue: No ]

Enrollment: 200
Study Start Date: January 2010
Study Completion Date: January 2013
Primary Completion Date: January 2013 (Final data collection date for primary outcome measure)
Hong Kong Chinese
Without a history of known intracranial pathologies.

Detailed Description:
As charted below.

Ages Eligible for Study:   21 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Hong Kong Chinese without a history of known intracranial pathologies

Inclusion Criteria:

  • Healthy adults aged between 21 and 65 years

Exclusion Criteria:

  • Contraindications to MRI
  • History of known intracranial pathologies
  Contacts and Locations
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Please refer to this study by its identifier: NCT01078506

Department of Surgery, The Chinese University of Hong Kong
Hong Kong, China
Sponsors and Collaborators
Chinese University of Hong Kong
Principal Investigator: George KC Wong Chinese University of Hong Kong
  More Information

No publications provided

Responsible Party: George KC Wong, Professor (Clinical), Chinese University of Hong Kong Identifier: NCT01078506     History of Changes
Other Study ID Numbers: GW006
Study First Received: February 26, 2010
Last Updated: April 22, 2013
Health Authority: Hong Kong: Joint CUHK-NTEC Clinical Research Ethics Committee

Keywords provided by Chinese University of Hong Kong:
intracranial aneurysm
magnetic resonance imaging

Additional relevant MeSH terms:
Intracranial Aneurysm
Brain Diseases
Cardiovascular Diseases
Central Nervous System Diseases
Cerebrovascular Disorders
Intracranial Arterial Diseases
Nervous System Diseases
Vascular Diseases processed this record on December 01, 2015