Corneal Endothelium Cell Loss After Cataract Extraction in Patients Taking Tamsulosin
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01076309|
Recruitment Status : Completed
First Posted : February 26, 2010
Last Update Posted : July 21, 2011
|Condition or disease|
Cataract surgery in patients taking Tamsulosin is regarded as more challenging for the surgeon because Intraoperative Floppy Iris Syndrome (IFIS) might occur. However, the question is whether this has any practical implication for the outcomes of surgery. In this study we investigate whether cornea is damage during surgery on Tamsulosin patient. In an observational study 30 cataract patients taking Tamsulosin is compared to 30 patients not taking Tamsulosin, but otherwise similar. Number of patients is based on power calculation.
Cornea is examined by specular microscopy.
|Study Type :||Observational|
|Actual Enrollment :||60 participants|
|Observational Model:||Case Control|
|Official Title:||Corneal Endothelium Cell Loss After Cataract Extraction in Patients Taking Systemic Sympathetic Alfa-1-a-antagonist Medication (Tamsulosin)|
|Study Start Date :||June 2009|
|Actual Primary Completion Date :||September 2010|
|Actual Study Completion Date :||September 2010|
Patients taking tamsulosin
Patients not taking tamsulosin.
- corneal endothelium cell loss [ Time Frame: 3 months ]Corneal endothelium cells was evaluated by specular microskopy before and 3 month post-operatively.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01076309
|Frederiksberg University Hospital|
|Frederiksberg, Denmark, 2000|