Predictive Factors of Clinical, Laboratory and Imaging Findings Routinely Used in Diagnosing Thyroid Cancer (TIR-2009-01)
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ClinicalTrials.gov Identifier: NCT01074684
Verified November 2015 by National Cancer Institute, Naples. Recruitment status was: Active, not recruiting
The purpose of this study is to describe the correlation between the cytohistology exam of patients undergoing thyroid surgery, and the predictive values of: suspicious clinical findings, preoperative thyroid imaging, and the incidence of thyroid cancer in cytologically negative nodes.
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Consecutive patients with palpable thyroid nodules with indication for surgery (positive cytology, 2 consecutive inconclusive cytologies, or negative cytology with at least 2 of the following: previous exposure to neck radiation, calcitonin greater than twice normal values, positive pentagastrin test, or irregular margins or hypoechogenicity on ultrasound.
Consecutive patients presenting for thyroid disease (palpable nodules)
Indication for surgery
Age > 18 years
Signed informed consent for surgery
Signed informed consent for data collection
Concurrent condition that contraindicates surgery
Clinical or radiologic evidence of locally advanced tumor
Clinical or radiologic evidence of metastatic lymph nodes or distant metastases