The Effect of Obesity on Growth Hormone Response to Anaerobic Exercise

The recruitment status of this study is unknown because the information has not been verified recently.

Verified March 2012 by Meir Medical Center.
Recruitment status was Recruiting

Sponsor:

Information provided by (Responsible Party):

Meir Medical Center

ClinicalTrials.gov Identifier:

NCT01070589

First received: February 17, 2010

Last updated: March 16, 2012

Last verified: March 2012

History of Changes

Purpose

The aim of the present study is to asses the effect of obesity on anaerobic exercise's growth hormone (GH) response.

Condition
Obesity


Study Type:	Observational
Study Design:	Observational Model: Case Control Time Perspective: Prospective
Official Title:	The Effect of Obesity on Growth Hormone Response to Anaerobic Exercise

Resource links provided by NLM:

MedlinePlus related topics: Exercise and Physical Fitness Hormones

U.S. FDA Resources

Further study details as provided by Meir Medical Center:


Estimated Enrollment:	24
Study Start Date:	February 2010
Estimated Study Completion Date:	July 2012
Estimated Primary Completion Date:	July 2012 (Final data collection date for primary outcome measure)

Groups/Cohorts
Group 1: Obese BMI>30
Group 2: control Group 2:Normal weight (BMI <25). age and gender matched.

Detailed Description:

Exercise is a potent physiological stimulator of growth hormone (GH) release. GH is an important factor in the distribution of fat and lean tissue in the body. Previous studies suggested that the GH response to aerobic exercise may be attenuated by obesity. The effect of obesity on GH response to anaerobic effort is unclear. The aim of the present study is to asses the effect of obesity on anaerobic exercise's GH response. We will recruit 12 obese (BMI > 30) healthy adults and 12 age and gender matched normal weight (BMI < 25) controls. All the participants will conduct a "wingate" anaerobic test (30 seconds of intense effort against resistance calculated by the individual's body weight). Blood sample for GH level will be collected at 5 different time (0, 20, 30, 40 and 60 minutes after the test). We will compare the GH response in the two groups.

Eligibility


Ages Eligible for Study:	18 Years to 40 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	Yes
Sampling Method:	Probability Sample

Study Population

Healthy female Age 18-40 years

Criteria

Inclusion Criteria:

Healthy female
Age 18-40

Exclusion Criteria:

Male
Age <18, >40
Heart, Liver, Kidney or Hypophyseal disease
Medications that may alter GH secretion (eg Steroids, Eltroxin)

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01070589

Contacts


Contact: Noa rakover klein, MD	972-77-4920014	noa.rakover@gmail.com

Locations


Israel
Meir Medical Center	Recruiting
Kfar Saba, Israel
Contact: Noa rakover klein, MD 974-9-7472630 NOA.KLEIN@clalit.org.il
Principal Investigator: Noa Klein, MD

Sponsors and Collaborators

Meir Medical Center

Investigators


Principal Investigator:	Allon Eliakim, MD	Meir Medical Center

More Information

No publications provided


Responsible Party:	Meir Medical Center
ClinicalTrials.gov Identifier:	NCT01070589 History of Changes
Other Study ID Numbers:	MMC01922009CTIL
Study First Received:	February 17, 2010
Last Updated:	March 16, 2012
Health Authority:	Israel: Ministry of Health

Keywords provided by Meir Medical Center:


Obesity Growth hormone secretion Anaerobic exercise

ClinicalTrials.gov processed this record on March 03, 2015

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