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The Effect of Obesity on Growth Hormone Response to Anaerobic Exercise
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified March 2012 by Meir Medical Center.
Recruitment status was: Recruiting
Recruitment status was: Recruiting
Sponsor:
Meir Medical Center
Information provided by (Responsible Party):
Meir Medical Center
ClinicalTrials.gov Identifier:
NCT01070589
First received: February 17, 2010
Last updated: March 16, 2012
Last verified: March 2012
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Purpose
The aim of the present study is to asses the effect of obesity on anaerobic exercise's growth hormone (GH) response.
| Condition |
|---|
| Obesity |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Prospective |
| Official Title: | The Effect of Obesity on Growth Hormone Response to Anaerobic Exercise |
Resource links provided by NLM:
Further study details as provided by Meir Medical Center:
| Estimated Enrollment: | 24 |
| Study Start Date: | February 2010 |
| Estimated Study Completion Date: | July 2012 |
| Estimated Primary Completion Date: | July 2012 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
Group 1: Obese
BMI>30
|
|
Group 2: control
Group 2:Normal weight (BMI <25). age and gender matched.
|
Detailed Description:
Exercise is a potent physiological stimulator of growth hormone (GH) release. GH is an important factor in the distribution of fat and lean tissue in the body. Previous studies suggested that the GH response to aerobic exercise may be attenuated by obesity. The effect of obesity on GH response to anaerobic effort is unclear. The aim of the present study is to asses the effect of obesity on anaerobic exercise's GH response. We will recruit 12 obese (BMI > 30) healthy adults and 12 age and gender matched normal weight (BMI < 25) controls. All the participants will conduct a "wingate" anaerobic test (30 seconds of intense effort against resistance calculated by the individual's body weight). Blood sample for GH level will be collected at 5 different time (0, 20, 30, 40 and 60 minutes after the test). We will compare the GH response in the two groups.
Eligibility| Ages Eligible for Study: | 18 Years to 40 Years (Adult) |
| Sexes Eligible for Study: | Female |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Probability Sample |
Study Population
Healthy female Age 18-40 years
Criteria
Inclusion Criteria:
- Healthy female
- Age 18-40
Exclusion Criteria:
- Male
- Age <18, >40
- Heart, Liver, Kidney or Hypophyseal disease
- Medications that may alter GH secretion (eg Steroids, Eltroxin)
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01070589
Please refer to this study by its ClinicalTrials.gov identifier: NCT01070589
Contacts
| Contact: Noa rakover klein, MD | 972-77-4920014 | noa.rakover@gmail.com |
Locations
| Israel | |
| Meir Medical Center | Recruiting |
| Kfar Saba, Israel | |
| Contact: Noa rakover klein, MD 974-9-7472630 NOA.KLEIN@clalit.org.il | |
| Principal Investigator: Noa Klein, MD | |
Sponsors and Collaborators
Meir Medical Center
Investigators
| Principal Investigator: | Allon Eliakim, MD | Meir Medical Center |
More Information
| Responsible Party: | Meir Medical Center |
| ClinicalTrials.gov Identifier: | NCT01070589 History of Changes |
| Other Study ID Numbers: |
MMC01922009CTIL |
| Study First Received: | February 17, 2010 |
| Last Updated: | March 16, 2012 |
Keywords provided by Meir Medical Center:
|
Obesity Growth hormone secretion Anaerobic exercise |
Additional relevant MeSH terms:
|
Obesity Overnutrition Nutrition Disorders Overweight Body Weight |
Signs and Symptoms Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Physiological Effects of Drugs |
ClinicalTrials.gov processed this record on July 19, 2017