Prognostic Value of Progesterone for In Vitro Fertilization (IVF) Outcome (PROG2)
|ClinicalTrials.gov Identifier: NCT01067664|
Recruitment Status : Completed
First Posted : February 11, 2010
Last Update Posted : October 18, 2013
This observational study attempts to investigate the potential role of serum progesterone levels on the day of hCG administration (thus, the end of the follicular phase) on the probability of pregnancy, in patients undergoing IVF with the use of GnRH antagonists and recombinant gonadotrophins.
There has been evidence, that increased serum levels of progesterone are associated with a decreased probability of pregnancy after IVF.
This study will attempt to explore the role of progesterone on the outcome of IVF, by closely monitoring its levels during the late follicular phase.
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||130 participants|
|Official Title:||The Effect of Serum Progesterone Levels on the Day of hCG Administration on the Probability of Pregnancy in Patients Treated by IVF Using GnRH Antagonists and Recombinant Gonadotrophins|
|Study Start Date :||May 2009|
|Primary Completion Date :||June 2013|
|Study Completion Date :||June 2013|
|Patients undergoing IVF with rFSH and GnRH antagonists|
- Clinical pregnancy, defined as ultrasound evidence of fetal heart activity at 6-8 weeks of gestation [ Time Frame: At 6-8 weeks of gestation ]
- Pregnancy (defined as a b-hCG> 25 IU/L) [ Time Frame: 12 days after embryo transfer ]
Biospecimen Retention: Samples Without DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01067664
|Unit for Human Reproduction, 1st Dept. of Obstetrics and Gynaecology, Medical School, Aristotle University of Thessaloniki|
|Principal Investigator:||Basil C Tarlatzis, MD, PhD||1st Dept. of Obstetrics and Gynaecology, Medical School, Aristotle University of Thessaloniki|
|Principal Investigator:||Christos A Venetis, MD, MSc||Unit for Human Reproduction, 1st Dept. of Obstetrics and Gynaecology, Medical School, Aristotle University of Thessaloniki|