Extubation Readiness and Neuroventilatory Efficiency After Acute Respiratory Failure
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|ClinicalTrials.gov Identifier: NCT01065428|
Recruitment Status : Completed
First Posted : February 9, 2010
Results First Posted : November 16, 2010
Last Update Posted : August 31, 2011
|Condition or disease||Phase|
|Respiratory Failure||Phase 1|
|Study Type :||Observational|
|Actual Enrollment :||52 participants|
|Official Title:||Department of Critical Care Medicine, Nanjing Zhong-Da Hospital, Southeast University School of Medicine, China; Department of Critical Care Medicine St. Michaels's Hospital, University of Toronto, Canada|
|Study Start Date :||December 2008|
|Primary Completion Date :||July 2010|
|Study Completion Date :||July 2010|
Weaning failure:(1) failed SBT; (2) reintubation and /or resumption of support following successful extubation; or (3) die 48h following extubation.
Weaning successful:extubation and the absence of ventilatory support 48 h following the extubation
- Neuroventilatory Efficiency (NVE) [ Time Frame: at 30 minutes of the spontaneous breathing trials (SBT) ]NVE is the ratio of tidal volume and diaphragm electrical activity (Vt/EAdi).It is a value describing how effective a patient's breathing is.
- Neuromechanical Efficiency (NME) [ Time Frame: at 30 minutes of the spontaneous breathing trials (SBT) ]NME is the ratio between inspiratory pressure generation and EAdi (Paw/EAdi).
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01065428
|Nanjing Zhong-Da Hospital|
|Nanjing, Jiangsu, China, 21009|
|Study Director:||Haibo Qiu, MD, Phd||Southeast University|