Bright Light: A Novel Treatment for Anxiety
|ClinicalTrials.gov Identifier: NCT01064700|
Recruitment Status : Completed
First Posted : February 8, 2010
Last Update Posted : February 8, 2010
The primary aim of this research was to examine the influence of bright light on anxiety in high-anxious young adults. In an acute exposure study, participants were randomly assigned to 45 min of either (1) bright light (3,000 lux) or (2) a placebo inactivated negative ion generator. Treatments were initiated ≤1 hr after awakening. At 10 min before and 30 min after the treatments, state anxiety, mood, and blood pressure were assessed.
Following the acute exposure study, participants performed a 5-week study. Following a a 1-week baseline, participants were randomly assigned to four weeks of daily exposure to either (1) bright light (45 min/day; 3,000 lux) or (2) placebo inactivated negative ion generator, which were initiated ≤1 hr after awakening. Before and after the experiment, clinical ratings were conducted with the Hamilton Anxiety Scale, the Hamilton Depression Scale, and the Clinical Global Impressions scale (CGI). Following baseline, and following each week of treatment, blood pressure, as well as questionnaires for state anxiety, depression, mood, sleep, and side effects were assessed.
|Condition or disease||Intervention/treatment||Phase|
|Anxiety Depression Sleep||Device: Litebook Bright Light Box Device: Litebook inactivated negation ion generator (the placebo)||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||33 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Triple (Participant, Investigator, Outcomes Assessor)|
|Official Title:||Bright Light: A Novel Treatment for Anxiety|
|Study Start Date :||October 2006|
|Actual Primary Completion Date :||December 2007|
|Actual Study Completion Date :||December 2007|
No Intervention: Baseline
1 week period, in which subjects followed usual schedule, though they were asked to maintain a fairly stable sleep schedule. The baseline period was used for comparison with the experimental intervention.
Experimental: Experimental Intervention
Randomized exposure to the 4-week experimental treatments.
Device: Litebook Bright Light Box
Four weeks of daily exposure to bright light (3,000 lux) for 45 min/day, beginning within 60 min of arising.
Other Name: PhototherapyDevice: Litebook inactivated negation ion generator (the placebo)
Four weeks of daily exposure to inactivated negative ion generator for 45 min/day, beginning within 60 min of arising
Other Name: Placebo
- Spielberger State Anxiety Inventory [ Time Frame: 5 weeks ]
- Hamilton Anxiety [ Time Frame: 5 weeks ]
- Beck Depression Inventory [ Time Frame: 5 weeks ]
- Pittsburgh Sleep Quality Inventory [ Time Frame: 5 weeks ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01064700
|United States, South Carolina|
|Chronobiology Lab, University of South Carolina|
|Columbia, South Carolina, United States, 29208|
|Principal Investigator:||Shawn D Youngstedt||University of Southern California|