An Epidemiological Study of Acute Coronary Syndromes in The Greek Population. The TARGET Study (TARGET)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01061086
Recruitment Status : Completed
First Posted : February 2, 2010
Last Update Posted : December 21, 2011
Hellenic Cardiovascular Research Society
Information provided by (Responsible Party):

Brief Summary:
This is a multicenter, 2-phase observational study of acute coronary syndromes (ACS) in Greece, designed to provide real world data on the risk factors of patients presenting to a hospital emergency department with an index event, as well as to depict the current management practices and outcomes of these clinical conditions in Greece.

Condition or disease
Acute Coronary Syndromes

Study Type : Observational
Actual Enrollment : 418 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: An Epidemiological Study of Acute Coronary Syndromes in The Greek Population
Study Start Date : January 2010
Actual Primary Completion Date : June 2010
Actual Study Completion Date : February 2011

Patients over 18 years old admitted to the hospital with Acute Coronary Syndrome.

Primary Outcome Measures :
  1. To evaluate the proportion of patients who are on target for LDL-C according to the 2004-updated NCEP ATPIII guidelines as calculated within the first 24-hours of hospital admission for an ACS. [ Time Frame: first visit - 1st day (cross-sectional part) ]
  2. To estimate the proportion of patients enrolled in the cross-sectional part of the study that experiences a Major Adverse Cardiovascular Event (MACE) within a 6-month follow-up period. [ Time Frame: follow up visit - 6th month (prospective part) ]

Secondary Outcome Measures :
  1. To estimate the proportion of patients admitted to the hospital with STEMI, NSTEMI and unstable angina. [ Time Frame: first visit - 1st day (cross-sectional part) ]
  2. To estimate the "pain-to-door-time" throughout different regions in Greece. [ Time Frame: first visit - 1st day (cross-sectional part) ]
  3. To estimate the time to first MACE and to estimate CV, non-CV and all cause mortality within the 6-month period following the index ACS event. [ Time Frame: follow up visit - 6th month (prospective part) ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Emergency Room

Inclusion Criteria:

  • Diagnosis of an ACS (STEMI, NSTEMI, UA).
  • Informed Consent

Exclusion Criteria:

  • Involvement in the planning and conduct of the study (applies to both AstraZeneca staff and staff at the study sites).
  • Participation in other clinical study in period between the index event and 6- month follow-up assessment with the exception of registering in registries or surveys not influencing the management of the ACS.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01061086

Research Site
Athens, Attiki, Greece
Research Site
Chania, Chanion, Greece
Research Site
Heraklion, Herakliou, Greece
Research Site
Ioannina, Ioanninon, Greece
Research Site
Ptolemaida, Kozani, Greece
Research Site
Larissa, Larrisis, Greece
Research Site
Volos, Magnisias, Greece
Research Site
Eddesa, Pella, Greece
Research Site
Komotini, Rodopi, Greece
Research Site
Chalkida, Greece
Research Site
Chios, Greece
Sponsors and Collaborators
Hellenic Cardiovascular Research Society
Study Director: Panagiotis Pontikis AstraZeneca

Responsible Party: AstraZeneca Identifier: NCT01061086     History of Changes
Other Study ID Numbers: NIS-CGR-DUM-2009/1
First Posted: February 2, 2010    Key Record Dates
Last Update Posted: December 21, 2011
Last Verified: December 2011

Keywords provided by AstraZeneca:
Acute Coronary Syndromes
Management of disease

Additional relevant MeSH terms:
Acute Coronary Syndrome
Pathologic Processes
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases