Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

This study is enrolling participants by invitation only.
Information provided by:
Xi’an Jiaotong University College of Medicine Identifier:
First received: February 1, 2010
Last updated: NA
Last verified: January 2010
History: No changes posted
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Irritable Bowel Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control

Resource links provided by NLM:

Further study details as provided by Xi’an Jiaotong University College of Medicine:

Estimated Enrollment: 60
Study Start Date: January 2010


Ages Eligible for Study:   18 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Outpatients in the second affiliated hospital of xi'an jiaotong university

Inclusion Criteria:

  • Patients fulfilling the Rome III criteria for IBS participated in the study -

Exclusion Criteria:

  • Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

Responsible Party: the second affiliated hospital of xi'an jiaotong university Identifier: NCT01060527     History of Changes
Other Study ID Numbers: xi'an JTU091202 
Study First Received: February 1, 2010
Last Updated: February 1, 2010
Health Authority: United States: Food and Drug Administration

Keywords provided by Xi’an Jiaotong University College of Medicine:
irritable bowel syndrome,protease activity,China

Additional relevant MeSH terms:
Irritable Bowel Syndrome
Colonic Diseases
Colonic Diseases, Functional
Digestive System Diseases
Gastrointestinal Diseases
Intestinal Diseases processed this record on May 24, 2016