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Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2010 by Health Science Center of Xi’an Jiaotong University.
Recruitment status was:  Enrolling by invitation
Information provided by:
Health Science Center of Xi’an Jiaotong University Identifier:
First received: February 1, 2010
Last updated: NA
Last verified: January 2010
History: No changes posted
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Irritable Bowel Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control

Resource links provided by NLM:

Further study details as provided by Health Science Center of Xi’an Jiaotong University:

Estimated Enrollment: 60
Study Start Date: January 2010


Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Outpatients in the second affiliated hospital of xi'an jiaotong university

Inclusion Criteria:

  • Patients fulfilling the Rome III criteria for IBS participated in the study -

Exclusion Criteria:

  • Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.
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No Contacts or Locations Provided
  More Information

Responsible Party: the second affiliated hospital of xi'an jiaotong university Identifier: NCT01060527     History of Changes
Other Study ID Numbers: xi'an JTU091202
Study First Received: February 1, 2010
Last Updated: February 1, 2010

Keywords provided by Health Science Center of Xi’an Jiaotong University:
irritable bowel syndrome,protease activity,China

Additional relevant MeSH terms:
Irritable Bowel Syndrome
Pathologic Processes
Colonic Diseases, Functional
Colonic Diseases
Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases processed this record on May 25, 2017