Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01060527
Recruitment Status : Unknown
Verified January 2010 by Health Science Center of Xi’an Jiaotong University.
Recruitment status was:  Enrolling by invitation
First Posted : February 2, 2010
Last Update Posted : February 2, 2010
Information provided by:
Health Science Center of Xi’an Jiaotong University

Brief Summary:
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Condition or disease
Irritable Bowel Syndrome

Study Type : Observational
Estimated Enrollment : 60 participants
Observational Model: Case Control
Study Start Date : January 2010


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Outpatients in the second affiliated hospital of xi'an jiaotong university

Inclusion Criteria:

  • Patients fulfilling the Rome III criteria for IBS participated in the study -

Exclusion Criteria:

  • Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.

Responsible Party: the second affiliated hospital of xi'an jiaotong university Identifier: NCT01060527     History of Changes
Other Study ID Numbers: xi'an JTU091202
First Posted: February 2, 2010    Key Record Dates
Last Update Posted: February 2, 2010
Last Verified: January 2010

Keywords provided by Health Science Center of Xi’an Jiaotong University:
irritable bowel syndrome,protease activity,China

Additional relevant MeSH terms:
Irritable Bowel Syndrome
Pathologic Processes
Colonic Diseases, Functional
Colonic Diseases
Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases