Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

This study is enrolling participants by invitation only.
Sponsor:
Information provided by:
Health Science Center of Xi’an Jiaotong University
ClinicalTrials.gov Identifier:
NCT01060527
First received: February 1, 2010
Last updated: NA
Last verified: January 2010
History: No changes posted
  Purpose
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Condition
Irritable Bowel Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control

Resource links provided by NLM:


Further study details as provided by Health Science Center of Xi’an Jiaotong University:

Estimated Enrollment: 60
Study Start Date: January 2010
Groups/Cohorts
IBS-D
IBS-C
Controll

  Eligibility

Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Outpatients in the second affiliated hospital of xi'an jiaotong university
Criteria

Inclusion Criteria:

  • Patients fulfilling the Rome III criteria for IBS participated in the study -

Exclusion Criteria:

  • Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

Responsible Party: the second affiliated hospital of xi'an jiaotong university
ClinicalTrials.gov Identifier: NCT01060527     History of Changes
Other Study ID Numbers: xi'an JTU091202 
Study First Received: February 1, 2010
Last Updated: February 1, 2010
Health Authority: United States: Food and Drug Administration

Keywords provided by Health Science Center of Xi’an Jiaotong University:
irritable bowel syndrome,protease activity,China

Additional relevant MeSH terms:
Syndrome
Irritable Bowel Syndrome
Disease
Pathologic Processes
Colonic Diseases, Functional
Colonic Diseases
Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases

ClinicalTrials.gov processed this record on August 30, 2016