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Enhancement and Restoring of Low Dose Abdominal CT Images

This study has been completed.
Sykehuset Buskerud HF
Information provided by (Responsible Party):
Lars Borgen, University of Oslo Identifier:
First received: January 21, 2010
Last updated: June 1, 2015
Last verified: November 2009
Through the rapid growth of multislice Computer Tomography (CT) imaging, radiation protection has become a major issue in the radiological community. Optimizing CT scanning is a key task when keeping the radiation doses as low as reasonable achievable (the ALARA principle). Post processing filters can improve and restore grainy and noisy low dose CT images by enhancing structure and reducing image noise. In our study of 10 patients, the investigators perform a preliminary evaluation of a novel post processing filter, which does picture element correlations in all three spatial dimensions. By comparing normal dose pictures with unprocessed low-dose pictures and pictures processed with two dimentional (2D) and three dimentional (3D) filters,the investigators will be able to assess the possible clinical value of the 3D filter. This project is collaboration between Buskerud Hospital (BU), Buskerud University College, Norwegian Radiation Protection Authority (NRPA) and Center for Medical Image Science and Visualization (CMIV). The project is part of the PhD of Lars Borgen.

Condition Intervention Phase
Radiation Protection Other: Using a 3 dimentional post processing filter Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Diagnostic
Official Title: Enhancement and Restoring of Low Dose Abdominal CT Images by a Novel Adaptive Nonlinear 3D Post Processing Filter - a Prospective Blinded Interventional Study

Further study details as provided by Lars Borgen, University of Oslo:

Primary Outcome Measures:
  • Rating of image quality [ Time Frame: 3-6 months ]

Enrollment: 12
Study Start Date: December 2009
Study Completion Date: December 2011
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: Unenhanced images
Enhanced images
Enhanced images
Other: Using a 3 dimentional post processing filter
Using a 3 dimentional post processing filter


Ages Eligible for Study:   60 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Outpatients, Male or female,Age above 60 years, Referred to our department for an abdominal CT with intravenous contrast.

Exclusion Criteria:

  • Abdominal diameter less than 80cm or larger than 100cm, Gross pancreatic pathology, Gross anatomic anomalies in the investigated region, Intolerance of intravenous contrast
  Contacts and Locations
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Please refer to this study by its identifier: NCT01059032

Buskerud Hospital
Drammen, Norway, 3014
Sponsors and Collaborators
Lars Borgen
Sykehuset Buskerud HF
  More Information

Responsible Party: Lars Borgen, MD, University of Oslo Identifier: NCT01059032     History of Changes
Other Study ID Numbers: 15017044793
Study First Received: January 21, 2010
Last Updated: June 1, 2015 processed this record on August 23, 2017