Effects of PGI2 Analogue Use on the Development of Chronic Allograft Nephropathy
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The purpose of this study is to evaluate the effect of Prostaglandin I2 analogue use on the development of chronic allograft nephropathy and changes in allograft function in prevalent renal transplant recipients
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Ages Eligible for Study:
20 Years to 50 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
prevalent renal transplant recipients 2 years after transplantation
no history of acute rejection
stable renal function
history of biopsy-proven chronic allograft nephropathy
history of biopsy-proven CNI nephrotoxicity
history of biopsy-proven or clinical acute rejection
unstable trough level of CNI or extremely low level of CNI