Compensatory Strategies Applied to Cognitive Impairment in Schizophrenia (CAT-Denmark)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01055509|
Recruitment Status : Completed
First Posted : January 25, 2010
Last Update Posted : June 28, 2013
|Condition or disease||Intervention/treatment|
|Schizophrenia||Behavioral: Cognitive Adaptation Training|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||65 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||Effectiveness of Cognitive Adaptation Training Applied to Cognitive Impairment in Schizophrenia - A Randomised Trial|
|Study Start Date :||January 2009|
|Primary Completion Date :||April 2011|
|Study Completion Date :||August 2011|
Experimental: Cognitive Adaptation Training
Cognitive adaptation training and treatment as usual
Behavioral: Cognitive Adaptation Training
All patients receive treatment as usual. Additionally, patients in the intervention arm receives training concerning solving concrete problems related to the patient's daily life using tools such as schedules, schemes and signs. Additional the patient can receive SMS messages or instructions for the use of schedules in cell-phones to prompt for activities. The intervention is conducted in the patients homes every 14th day in a period of six months.
No Intervention: Treatment as ususal
Pharmacological treatment, weekly contact to professionals (often in patient's homes), psychoeducation, social skill training in groups and psychosocial intervention with relatives.
- Changes in Social functioning assessed by Global Assessment of Function test and Health of the Nation Outcome Scales item 9-12 concerning social problems. [ Time Frame: Baseline, six month and nine month. ]The effect of intervention on primary outcome are invetigated as longitudinal data at six and nine month. The data are analysed using mixed models.
- Changes in Social Functioning using Camberwell Assessment of Need questionnaire. Symptoms using Positive and Negative Syndrome Scale. Quality of Life using Lehman Quality of Life Interview-brief version. Relapse and frequency of hospitalization. [ Time Frame: Baseline, six month and nine month. ]The effect of intervention on secondary outcome are invetigated as longitudinal data at six and nine month. The data are analysed using mixed models. However, relapse are analysed using survival analysis.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01055509
|Early Intervention Team|
|Aabenraa, Denmark, DK.6200|
|Schizophrenic Clinic, Psychiatric Department in Esbjerg and Ribe|
|Esbjerg N, Denmark, DK-6715|
|Early Intervention Team|
|Odense, Denmark, Dk-5000|
|Principal Investigator:||Lise Hounsgaard, PhD||Research Unit of Nursing|