Effect of Exercise-based Rehabilitation on Circulatory Functions in Patients With Diastolic Heart Failure
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ClinicalTrials.gov Identifier: NCT01053091 |
Recruitment Status
:
Completed
First Posted
: January 21, 2010
Last Update Posted
: February 26, 2015
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Heart Failure | Behavioral: exercise | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 120 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | Effect of Exercise-based Rehabilitation on Circulatory Functions in Patients With Diastolic Heart Failure |
Study Start Date : | October 2009 |
Actual Primary Completion Date : | December 2011 |
Actual Study Completion Date : | December 2013 |
Arm | Intervention/treatment |
---|---|
Experimental: Exercise
exercise
|
Behavioral: exercise
The trained subjects will be trained on a bicycle ergometer at about 60-70%of heart rate reserve for 35-55 minutes (that will include 10-min warm-up, 15-35-min main exercise, and 10-min cool-down) per day, 3 days per week for 12 weeks
Other Name: behavioral
|
No Intervention: Control
control
|
- physical fitness including cardiovascular functions, oxygen transport and utilization of exercising skeletal muscles and hemodynamics [ Time Frame: one year ]
- blood cell parameters, RBC deformity and aggregation, plasma biomarkers of myocardial damage, and thrombotic factors/reactions change between pre-ex and post-ex. [ Time Frame: one year ]

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Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- cardiac event with optimal medial treatment within 3 months and have 4 more weeks spared from heart disease attack or major cardiac procedure.
- LVEF>50%
Exclusion Criteria:
- unstable angina pectoris,
- uncompensated heart failure,
- myocardial infarction during the past 4 weeks,
- complex ventricular arrhythmias,
- orthopedic or neurological limitations to exercise.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01053091
Taiwan | |
Department of Physical Medicine and Rehabilitation of Keelung Chang Gung Memorial hospital | |
Keelung, Taiwan, 104 |
Principal Investigator: | T'sang-T'ang Hsieh, MD | Chang Gung Memorial Hospital |
Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Fu Tieh Cheng, attending physician, Chang Gung Memorial Hospital |
ClinicalTrials.gov Identifier: | NCT01053091 History of Changes |
Other Study ID Numbers: |
98-1374B |
First Posted: | January 21, 2010 Key Record Dates |
Last Update Posted: | February 26, 2015 |
Last Verified: | February 2015 |
Keywords provided by Fu Tieh Cheng, Chang Gung Memorial Hospital:
exercise-base rehabilitation diastolic heart failure cardiovascular function aerobic fitness |
Additional relevant MeSH terms:
Heart Failure Heart Failure, Diastolic Heart Diseases Cardiovascular Diseases |