The Cyclocapnic Method for Measurement of Chemosensitivity
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|ClinicalTrials.gov Identifier: NCT01049256|
Recruitment Status : Unknown
Verified January 2010 by Imperial College London.
Recruitment status was: Recruiting
First Posted : January 14, 2010
Last Update Posted : January 14, 2010
We aim to test our method for measuring chemosensitivity (the ventilatory response to a change in carbon dioxide), which uses sinusoidal carbon dioxide stimuli.
- Carbon dioxide sensitivity is dependent on the cycle time over which we administer the gas (frequency).
- Chemoreflex gain decreases as deadspace increases.
|Condition or disease||Intervention/treatment||Phase|
|Periodic Breathing Heart Failure||Other: carbon dioxide||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||45 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Developing an Improved Measure of Chemosensitivity for the Study of Periodic Breathing in Heart Failure: the Cyclocapnic Method|
|Study Start Date :||January 2008|
|Estimated Primary Completion Date :||April 2010|
|Estimated Study Completion Date :||October 2010|
- Other: carbon dioxide
sinusoidal carbon dioxide administration
- Chemoreflex gain as measured by cyclocapnic method [ Time Frame: every minute ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01049256
|Contact: Darrel P Francis, MD||+44 207 594 firstname.lastname@example.org|
|St Mary's Hospital||Recruiting|
|London, United Kingdom, W2 1LA|
|Contact: Resham Baruah, MB BS 020 75941027 email@example.com|
|Contact: Darrel P Francis, MD +44 207 594 1093 firstname.lastname@example.org|
|Principal Investigator:||Darrel P Francis, MD||Imperial College London|