Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

This study is currently recruiting participants. (see Contacts and Locations)
Verified February 2015 by Stanford University
National Institutes of Health (NIH)
Information provided by (Responsible Party):
Stanford University Identifier:
First received: January 11, 2010
Last updated: February 3, 2015
Last verified: February 2015
Our research of the biology of upper gastrointestinal cancers involves the study of tissue samples and cells from biopsies of persons with gastric or esophageal cancer or blood samples from upper gastrointestinal cancer patients and persons at high inherited risk for these cancers. We hope to learn the role genes and proteins play in the development of gastric and esophageal cancer.

Condition Intervention
Stomach Cancer
Gastro-Esophageal(GE) Junction Cancer
Gastric (Stomach) Cancer
Esophageal Cancer
Gastrointestinal Stromal Tumor (GIST)
Procedure: Blood draw
Procedure: Tissue tumor biopsy

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

Resource links provided by NLM:

Further study details as provided by Stanford University:

Primary Outcome Measures:
  • p53 activity by routine pathologic analysis [ Time Frame: time of collection ] [ Designated as safety issue: No ]
  • NER activity by routine pathologic analysis [ Time Frame: time of collection ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA
blood, tumor

Estimated Enrollment: 100
Study Start Date: August 2002
Estimated Study Completion Date: December 2015
Estimated Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adults with gastric or esophageal cancer

Inclusion Criteria:1. Over 18 2. Diagnosed with gastric or esophageal cancer OR at an increased hereditary risk for upper GI cancer

Exclusion Criteria:1. Under 18 2. No family or personal history of gastric or esophageal cancer

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01048281

Contact: Meredith Mills (650) 724-5223

United States, California
Stanford University School of Medicine Recruiting
Stanford, California, United States, 94305
Contact: Meredith Mills    650-724-5223   
Principal Investigator: James M Ford         
Sub-Investigator: Hanlee P. Ji         
Sub-Investigator: Vandana Bhardwaj Sharma         
Sponsors and Collaborators
Stanford University
National Institutes of Health (NIH)
Principal Investigator: James M Ford Stanford University
  More Information

Responsible Party: Stanford University Identifier: NCT01048281     History of Changes
Other Study ID Numbers: GIUPR0001  76274  CA109190  SU-11022007-787 
Study First Received: January 11, 2010
Last Updated: February 3, 2015
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Esophageal Neoplasms
Gastrointestinal Stromal Tumors
Stomach Neoplasms
Digestive System Diseases
Digestive System Neoplasms
Esophageal Diseases
Gastrointestinal Diseases
Gastrointestinal Neoplasms
Head and Neck Neoplasms
Neoplasms by Histologic Type
Neoplasms by Site
Neoplasms, Connective Tissue
Neoplasms, Connective and Soft Tissue
Stomach Diseases processed this record on May 23, 2016