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Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

This study is currently recruiting participants.

See

Contacts and Locations

Verified July 2016 by Stanford University

Sponsor:

ClinicalTrials.gov Identifier:

NCT01048281

First Posted: January 13, 2010

Last Update Posted: July 14, 2016

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

Collaborator:

National Institutes of Health (NIH)

Information provided by (Responsible Party):

Stanford University

Purpose

Our research of the biology of upper gastrointestinal cancers involves the study of tissue samples and cells from biopsies of persons with gastric or esophageal cancer or blood samples from upper gastrointestinal cancer patients and persons at high inherited risk for these cancers. We hope to learn the role genes and proteins play in the development of gastric and esophageal cancer.

Condition	Intervention
Stomach Cancer Gastro-Esophageal(GE) Junction Cancer Gastric (Stomach) Cancer Esophageal Cancer Gastrointestinal Stromal Tumor (GIST)	Procedure: Blood draw Procedure: Tissue tumor biopsy


Study Type:	Observational
Study Design:	Observational Model: Cohort Time Perspective: Prospective
Official Title:	Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

Resource links provided by NLM:

Genetics Home Reference related topics: gastrointestinal stromal tumor

Genetic and Rare Diseases Information Center resources: Gastrointestinal Stromal Tumors Stomach Cancer Esophageal Cancer

U.S. FDA Resources

Further study details as provided by Stanford University:

Primary Outcome Measures:

p53 activity by routine pathologic analysis [ Time Frame: time of collection ]
NER activity by routine pathologic analysis [ Time Frame: time of collection ]

Biospecimen Retention: Samples With DNA

blood, tumor


Estimated Enrollment:	100
Study Start Date:	August 2002
Estimated Study Completion Date:	January 2099
Estimated Primary Completion Date:	January 2099 (Final data collection date for primary outcome measure)

Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:	18 Years and older (Adult, Senior)
Sexes Eligible for Study:	All
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Adults with gastric or esophageal cancer

Criteria

Inclusion Criteria:1. Over 18 2. Diagnosed with gastric or esophageal cancer OR at an increased hereditary risk for upper GI cancer

Exclusion Criteria:1. Under 18 2. No family or personal history of gastric or esophageal cancer

Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01048281

Contacts


Contact: Meredith Mills	(650) 724-5223	bluett@stanford.edu

Locations


United States, California
Stanford University School of Medicine	Recruiting
Stanford, California, United States, 94305
Contact: Meredith Mills 650-724-5223 bluett@stanford.edu
Principal Investigator: James M Ford
Sub-Investigator: Hanlee P. Ji
Sub-Investigator: Vandana Bhardwaj Sharma

Sponsors and Collaborators

Stanford University

National Institutes of Health (NIH)

Investigators


Principal Investigator:	James M Ford	Stanford University

More Information


Responsible Party:	Stanford University
ClinicalTrials.gov Identifier:	NCT01048281 History of Changes
Other Study ID Numbers:	GIUPR0001 76274 ( Other Identifier: Stanford University Alternate IRB Approval Number ) CA109190 ( Other Identifier: NIH ) SU-11022007-787 ( Other Identifier: Stanford University )
First Submitted:	January 11, 2010
First Posted:	January 13, 2010
Last Update Posted:	July 14, 2016
Last Verified:	July 2016

Additional relevant MeSH terms:


Esophageal Neoplasms Gastrointestinal Stromal Tumors Stomach Neoplasms Gastrointestinal Neoplasms Digestive System Neoplasms Neoplasms by Site Neoplasms Head and Neck Neoplasms	Digestive System Diseases Esophageal Diseases Gastrointestinal Diseases Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue Neoplasms by Histologic Type Stomach Diseases

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