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Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
This study is currently recruiting participants.
Verified July 2016 by Stanford University
Sponsor:
Stanford University
Collaborator:
National Institutes of Health (NIH)
Information provided by (Responsible Party):
Stanford University
ClinicalTrials.gov Identifier:
NCT01048281
First received: January 11, 2010
Last updated: July 12, 2016
Last verified: July 2016
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Purpose
Our research of the biology of upper gastrointestinal cancers involves the study of tissue samples and cells from biopsies of persons with gastric or esophageal cancer or blood samples from upper gastrointestinal cancer patients and persons at high inherited risk for these cancers. We hope to learn the role genes and proteins play in the development of gastric and esophageal cancer.
| Condition | Intervention |
|---|---|
| Stomach Cancer Gastro-Esophageal(GE) Junction Cancer Gastric (Stomach) Cancer Esophageal Cancer Gastrointestinal Stromal Tumor (GIST) | Procedure: Blood draw Procedure: Tissue tumor biopsy |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma |
Resource links provided by NLM:
Genetics Home Reference related topics:
gastrointestinal stromal tumor
Genetic and Rare Diseases Information Center resources:
Stomach Cancer
Esophageal Cancer
Gastrointestinal Stromal Tumors
U.S. FDA Resources
Further study details as provided by Stanford University:
Primary Outcome Measures:
- p53 activity by routine pathologic analysis [ Time Frame: time of collection ]
- NER activity by routine pathologic analysis [ Time Frame: time of collection ]
Biospecimen Retention: Samples With DNA
blood, tumor
| Estimated Enrollment: | 100 |
| Study Start Date: | August 2002 |
| Estimated Study Completion Date: | January 2099 |
| Estimated Primary Completion Date: | January 2099 (Final data collection date for primary outcome measure) |
Eligibility| Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
Adults with gastric or esophageal cancer
Criteria
Inclusion Criteria:1. Over 18 2. Diagnosed with gastric or esophageal cancer OR at an increased hereditary risk for upper GI cancer
Exclusion Criteria:1. Under 18 2. No family or personal history of gastric or esophageal cancer
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01048281
Please refer to this study by its ClinicalTrials.gov identifier: NCT01048281
Contacts
| Contact: Meredith Mills | (650) 724-5223 | bluett@stanford.edu |
Locations
| United States, California | |
| Stanford University School of Medicine | Recruiting |
| Stanford, California, United States, 94305 | |
| Contact: Meredith Mills 650-724-5223 bluett@stanford.edu | |
| Principal Investigator: James M Ford | |
| Sub-Investigator: Hanlee P. Ji | |
| Sub-Investigator: Vandana Bhardwaj Sharma | |
Sponsors and Collaborators
Stanford University
National Institutes of Health (NIH)
Investigators
| Principal Investigator: | James M Ford | Stanford University |
More Information
| Responsible Party: | Stanford University |
| ClinicalTrials.gov Identifier: | NCT01048281 History of Changes |
| Other Study ID Numbers: |
GIUPR0001 76274 ( Other Identifier: Stanford University Alternate IRB Approval Number ) CA109190 ( Other Identifier: NIH ) SU-11022007-787 ( Other Identifier: Stanford University ) |
| Study First Received: | January 11, 2010 |
| Last Updated: | July 12, 2016 |
Additional relevant MeSH terms:
|
Esophageal Neoplasms Gastrointestinal Stromal Tumors Stomach Neoplasms Gastrointestinal Neoplasms Digestive System Neoplasms Neoplasms by Site Neoplasms Head and Neck Neoplasms |
Digestive System Diseases Esophageal Diseases Gastrointestinal Diseases Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue Neoplasms by Histologic Type Stomach Diseases |
ClinicalTrials.gov processed this record on June 22, 2017