Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

This study is currently recruiting participants. (see Contacts and Locations)

Verified July 2016 by Stanford University

Sponsor:

Collaborator:

National Institutes of Health (NIH)

Information provided by (Responsible Party):

Stanford University

ClinicalTrials.gov Identifier:

NCT01048281

First received: January 11, 2010

Last updated: July 12, 2016

Last verified: July 2016

History of Changes

Purpose

Our research of the biology of upper gastrointestinal cancers involves the study of tissue samples and cells from biopsies of persons with gastric or esophageal cancer or blood samples from upper gastrointestinal cancer patients and persons at high inherited risk for these cancers. We hope to learn the role genes and proteins play in the development of gastric and esophageal cancer.

Condition	Intervention
Stomach Cancer Gastro-Esophageal(GE) Junction Cancer Gastric (Stomach) Cancer Esophageal Cancer Gastrointestinal Stromal Tumor (GIST)	Procedure: Blood draw Procedure: Tissue tumor biopsy


Study Type:	Observational
Study Design:	Observational Model: Cohort Time Perspective: Prospective
Official Title:	Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

Resource links provided by NLM:

Genetics Home Reference related topics: gastrointestinal stromal tumor

MedlinePlus related topics: Cancer Esophageal Cancer

Genetic and Rare Diseases Information Center resources: Esophageal Cancer Stomach Cancer Gastrointestinal Stromal Tumors

U.S. FDA Resources

Further study details as provided by Stanford University:

Primary Outcome Measures:

p53 activity by routine pathologic analysis [ Time Frame: time of collection ] [ Designated as safety issue: No ]
NER activity by routine pathologic analysis [ Time Frame: time of collection ] [ Designated as safety issue: No ]

Biospecimen Retention: Samples With DNA

blood, tumor


Estimated Enrollment:	100
Study Start Date:	August 2002
Estimated Study Completion Date:	January 2099
Estimated Primary Completion Date:	January 2099 (Final data collection date for primary outcome measure)

Eligibility


Ages Eligible for Study:	18 Years and older (Adult, Senior)
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Adults with gastric or esophageal cancer

Criteria

Inclusion Criteria:1. Over 18 2. Diagnosed with gastric or esophageal cancer OR at an increased hereditary risk for upper GI cancer

Exclusion Criteria:1. Under 18 2. No family or personal history of gastric or esophageal cancer

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01048281

Contacts


Contact: Meredith Mills	(650) 724-5223	bluett@stanford.edu

Locations


United States, California
Stanford University School of Medicine	Recruiting
Stanford, California, United States, 94305
Contact: Meredith Mills 650-724-5223 bluett@stanford.edu
Principal Investigator: James M Ford
Sub-Investigator: Hanlee P. Ji
Sub-Investigator: Vandana Bhardwaj Sharma

Sponsors and Collaborators

Stanford University

National Institutes of Health (NIH)

Investigators


Principal Investigator:	James M Ford	Stanford University

More Information


Responsible Party:	Stanford University
ClinicalTrials.gov Identifier:	NCT01048281 History of Changes
Other Study ID Numbers:	GIUPR0001 76274 CA109190 SU-11022007-787
Study First Received:	January 11, 2010
Last Updated:	July 12, 2016
Health Authority:	United States: Institutional Review Board

Additional relevant MeSH terms:


Esophageal Neoplasms Gastrointestinal Stromal Tumors Stomach Neoplasms Gastrointestinal Neoplasms Digestive System Neoplasms Neoplasms by Site Neoplasms Head and Neck Neoplasms	Digestive System Diseases Esophageal Diseases Gastrointestinal Diseases Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue Neoplasms by Histologic Type Stomach Diseases

ClinicalTrials.gov processed this record on September 23, 2016

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