Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
This study is currently recruiting participants.
(see Contacts and Locations)
Verified February 2015 by Stanford University
Sponsor:
Stanford University
Collaborator:
Information provided by (Responsible Party):
Stanford University
ClinicalTrials.gov Identifier:
NCT01048281
First received: January 11, 2010
Last updated: February 3, 2015
Last verified: February 2015
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Purpose
Our research of the biology of upper gastrointestinal cancers involves the study of tissue samples and cells from biopsies of persons with gastric or esophageal cancer or blood samples from upper gastrointestinal cancer patients and persons at high inherited risk for these cancers. We hope to learn the role genes and proteins play in the development of gastric and esophageal cancer.
| Condition | Intervention |
|---|---|
|
Stomach Cancer Gastro-Esophageal(GE) Junction Cancer Gastric (Stomach) Cancer Esophageal Cancer Gastrointestinal Stromal Tumor (GIST) |
Procedure: Blood draw Procedure: Tissue tumor biopsy |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma |
Resource links provided by NLM:
Genetics Home Reference related topics:
gastrointestinal stromal tumor
MedlinePlus related topics:
Cancer
Genetic and Rare Diseases Information Center resources:
Esophageal Cancer
Gastrointestinal Stromal Tumors
Stomach Carcinoma
U.S. FDA Resources
Further study details as provided by Stanford University:
Primary Outcome Measures:
- p53 activity by routine pathologic analysis [ Time Frame: time of collection ] [ Designated as safety issue: No ]
- NER activity by routine pathologic analysis [ Time Frame: time of collection ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
blood, tumor
| Estimated Enrollment: | 100 |
| Study Start Date: | August 2002 |
| Estimated Study Completion Date: | December 2015 |
| Estimated Primary Completion Date: | December 2015 (Final data collection date for primary outcome measure) |
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
Adults with gastric or esophageal cancer
Criteria
Inclusion Criteria:1. Over 18 2. Diagnosed with gastric or esophageal cancer OR at an increased hereditary risk for upper GI cancer
Exclusion Criteria:1. Under 18 2. No family or personal history of gastric or esophageal cancer
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01048281
Please refer to this study by its ClinicalTrials.gov identifier: NCT01048281
Contacts
| Contact: Meredith Mills | (650) 724-5223 | bluett@stanford.edu |
Locations
| United States, California | |
| Stanford University School of Medicine | Recruiting |
| Stanford, California, United States, 94305 | |
| Contact: Meredith Mills 650-724-5223 bluett@stanford.edu | |
| Principal Investigator: James M Ford | |
| Sub-Investigator: Hanlee P. Ji | |
| Sub-Investigator: Vandana Bhardwaj Sharma | |
Sponsors and Collaborators
Stanford University
Investigators
| Principal Investigator: | James M Ford | Stanford University |
More Information
No publications provided
| Responsible Party: | Stanford University |
| ClinicalTrials.gov Identifier: | NCT01048281 History of Changes |
| Other Study ID Numbers: | GIUPR0001, 76274, CA109190, SU-11022007-787 |
| Study First Received: | January 11, 2010 |
| Last Updated: | February 3, 2015 |
| Health Authority: | United States: Institutional Review Board |
Additional relevant MeSH terms:
|
Gastrointestinal Stromal Tumors Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms |
Neoplasms Neoplasms by Histologic Type Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue |
ClinicalTrials.gov processed this record on March 03, 2015