Management of Postoperative Pain Following Total Knee Arthroplasty by Using Acupuncture-moxibustion Therapy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01047384
Recruitment Status : Completed
First Posted : January 12, 2010
Last Update Posted : May 21, 2014
Information provided by (Responsible Party):
Chang Gung Memorial Hospital

Brief Summary:

Orthopedic surgery is reportedly among the most painful surgical procedures. Surgical damage following major orthopedic surgery often involves a large, deep incision with considerable tissue dissection and muscle, bone, and vascular exposure. Post-operative pain after such surgery is exacerbated on movement or by reflex spasms of the muscles, which may delay mobilization, reduce satisfaction, prolong hospitalization, and possibly increase medical costs.

We design a prospective randomized study for postoperative pain control following total knee arthroplasty.

Condition or disease Intervention/treatment Phase
Osteoarthritis, Knee Procedure: acupuncture-moxibustion therapy Procedure: Regular therapy Phase 2 Phase 3

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 100 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Treatment
Study Start Date : January 2010
Actual Primary Completion Date : June 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Acupuncture

Arm Intervention/treatment
Experimental: Experimental
acupuncture-moxibustion therapy
Procedure: acupuncture-moxibustion therapy
Active Comparator: Regular therapy
Regular therapy
Procedure: Regular therapy

Primary Outcome Measures :
  1. Pain VAS score [ Time Frame: pre-operaton, immediately post operation, postop 6hrs, postop 12hrs, postop 18hrs, postop 24hrs, post op 48hrs, postop 72hrs ]

Secondary Outcome Measures :
  1. Functional score: SF-36 [ Time Frame: Pre-operation, immediately post-operation, postop 6 weeks, postop 12 weeks ]

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • diagnosed for surgery of osteoarthritis of knee
  • ability to tolerate surgery under general anesthesia.

Exclusion Criteria:

  • refusal or the lack of mental ability to provide informed consent
  • neuropathic pain or sensory disorders in the leg requiring surgery
  • previous surgery of the knee joint
  • coagulation abnormalities
  • chronic opioid users
  • known history of intolerance to acupuncture-moxibustion therapy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01047384

Chang Gung Memorial Hospital
Kweishian, Taoyuan, Taiwan, 333
Sponsors and Collaborators
Chang Gung Memorial Hospital

Responsible Party: Chang Gung Memorial Hospital Identifier: NCT01047384     History of Changes
Other Study ID Numbers: acupuncture
First Posted: January 12, 2010    Key Record Dates
Last Update Posted: May 21, 2014
Last Verified: January 2010

Additional relevant MeSH terms:
Osteoarthritis, Knee
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases