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Plain Magnetic Resonance (MR) in the Assessment of Patients With Acute Abdomen

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ClinicalTrials.gov Identifier: NCT01044173
Recruitment Status : Withdrawn
First Posted : January 7, 2010
Last Update Posted : January 31, 2017
Information provided by (Responsible Party):
Jens Maier, Zealand University Hospital

Brief Summary:
At present, CT is the gold standard in the assessment of patients with acute abdomen. Yet, one CT of the abdomen exposes patients to a radiation dose equivalent to several years of background radiation. MR can be expected to yield the same information without ionizing radiation, but tends to be more time consuming. In this study, patients with nontraumatic acute abdominal pain referred to CT of the abdomen by the department of surgery will also have performed an additional MR scan covering the entire abdomen with few fast imaging sequences in approximately 15min. CT is the diagnostic test. The MR scan is only used for scientific purposes. It will be evaluated by a radiologist blinded for the results of the CT scan. Fourteen days after admission, a final diagnosis is established based on clinical, peroperative, pathological and lab. findings. The performance of CT and MR will then be compared. The investigators hypothesize that MR can provide a diagnostic accuracy comparable to CT.

Condition or disease Intervention/treatment
Acute Abdomen Device: MR scan

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 0 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Assessment of Patients With Nontraumatic Acute Abdominal Pain With Plain MR of the Abdomen - a Comparison With CT
Study Start Date : October 2011
Estimated Primary Completion Date : September 2012
Study Completion Date : October 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Abdominal Pain
U.S. FDA Resources

Intervention Details:
    Device: MR scan
    axial and coronal free breathing HASTE sequences 3D T1 weighted gradient echo breathhold

Primary Outcome Measures :
  1. diagnostic accuracy of CT vs. MR [ Time Frame: 14 days ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Signed informed consent form
  • Age > 18 years old
  • Nontraumatic acute abdomen
  • Weight < 120kg
  • Can keep apnoea for 15s
  • Surgeon in charge considers patient fit for participation in study

Exclusion Criteria:

  • Contraindications of MRI
  • Suspicion of acute vascular disease
  • Severe cardial or pulmonal insufficiency
  • Pregnancy
  • Untreated psychiatric illness

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01044173

Koege Sygehus
Koege, Denmark, DK4600
Sponsors and Collaborators
Zealand University Hospital
Principal Investigator: Thomas Jørgensen, MD Zealand University Hospital
Study Director: Jens Maier, MD Zealand University Hospital

Responsible Party: Jens Maier, overlæge, radiologisk afdeling, Køge sygehus, Zealand University Hospital
ClinicalTrials.gov Identifier: NCT01044173     History of Changes
Other Study ID Numbers: N-20090033
First Posted: January 7, 2010    Key Record Dates
Last Update Posted: January 31, 2017
Last Verified: January 2017

Keywords provided by Jens Maier, Zealand University Hospital:
acute abdomen
fast imaging

Additional relevant MeSH terms:
Abdomen, Acute
Abdominal Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Signs and Symptoms, Digestive