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The Effects of Gum Chewing on Energy Intake and Expenditure

This study has been completed.
The Obesity Society
Information provided by (Responsible Party):
University of Wisconsin, Madison Identifier:
First received: December 15, 2009
Last updated: October 6, 2015
Last verified: October 2015
The purpose of this study is to determine if chewing gum increases energy expenditure and decreases food intake.

Condition Intervention
Other: Chewing gum
Other: Water

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: The Effects of Gum Chewing on Energy Intake and Expenditure

Further study details as provided by University of Wisconsin, Madison:

Primary Outcome Measures:
  • Change in body composition [ Time Frame: Baseline and end of study (6 weeks) ]

Enrollment: 31
Study Start Date: September 2008
Study Completion Date: January 2011
Arms Assigned Interventions
Experimental: Chewing gum Other: Chewing gum
Subjects were instructed to chew gum at least 6 times a day in an effort to reduce snacking.
Placebo Comparator: Water Other: Water
Subjects were instructed to drink 8 oz of water at least 6 times a day in an effort to reduce snacking.


Ages Eligible for Study:   18 Years to 38 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • BMI 27-37, between the ages of 18 and 38

Exclusion Criteria:

  • History of chronic disease (e.g. liver, kidney, or heart disease, or diabetes)
  • Medications that affect energy expenditure, appetite, or body composition (e.g. antidepressants, beta blockers, antipsychotic, or weight loss medications)
  • A history of irregular menstrual cycles in women (indication of onset of menopause or other metabolic disturbances such as polycystic ovary syndrome)
  • A history of phenylketonuria (PKU)
  • Symptoms of depression
  • A history of eating disorders
  • Concurrent participation in a weight loss program
  • Cigarette smoking or other tobacco use
  • Jaw problems such as temporomandibular joint disorder (TMJ)
  • Allergies to any of the common components in gum (sweeteners, mint flavors, etc)
  • Heavy gum chewing prior to study ( > 3 times per week)
  • Pregnancy or lactation.
  Contacts and Locations
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Please refer to this study by its identifier: NCT01043471

United States, Wisconsin
University of Wisconsin-Madison
Madison, Wisconsin, United States, 53792
Sponsors and Collaborators
University of Wisconsin, Madison
The Obesity Society
Principal Investigator: Leah D Whigham, PhD Board of Regents of the University of Wisconsin System
  More Information

Responsible Party: University of Wisconsin, Madison Identifier: NCT01043471     History of Changes
Other Study ID Numbers: H-2007-0342
Study First Received: December 15, 2009
Last Updated: October 6, 2015

Keywords provided by University of Wisconsin, Madison:
Obesity processed this record on May 24, 2017