Optimal Timing For Embryo Transfer For Low Responder Patients

This study has been terminated.
(Difficulty in recruiting patients)
Sponsor:
Information provided by (Responsible Party):
Amir Weiss, HaEmek Medical Center, Israel
ClinicalTrials.gov Identifier:
NCT01040247
First received: December 28, 2009
Last updated: June 21, 2015
Last verified: June 2015
  Purpose
Women undergoing in vitro fertilization (IVF) therapy, who are low responder and agree to enter the trial will be randomized to a study group, for whom embryo transfer will be done on the same day as oocyte aspiration and fertilization; and a control group for whom embryo transfer will be performed 48 to 72 hours later, as is the current accepted practice.

Condition Intervention
Infertility
Other: Embryo Transfer

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment

Resource links provided by NLM:


Further study details as provided by HaEmek Medical Center, Israel:

Primary Outcome Measures:
  • Pregnancy [ Time Frame: 14 days ] [ Designated as safety issue: No ]

Enrollment: 20
Study Start Date: November 2009
Study Completion Date: March 2011
Primary Completion Date: March 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Day 0 Embryo Transfer
Embryo transfer will be performed on the same day as oocyte aspiration and fertilization
Other: Embryo Transfer
In the study group embryo transfer will be performed on the day of oocyte aspiration and fertilization while in the control group it will be done 2 or 3 days later as is common practice.
Active Comparator: Day 2,3 Embryo Transfer
Embryo Transfer will be performed 2 or 3 days after oocyte aspiration and fertilization
Other: Embryo Transfer
In the study group embryo transfer will be performed on the day of oocyte aspiration and fertilization while in the control group it will be done 2 or 3 days later as is common practice.

  Eligibility

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patient undergoing IVF
  • Number of mature oocytes equal to or lesser than the maximum number of embryos intended for transfer

Exclusion Criteria:

  • Patient nor consenting
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01040247

Locations
Israel
HaEmek Medical Center
Afula, Israel
Sponsors and Collaborators
HaEmek Medical Center, Israel
  More Information

Responsible Party: Amir Weiss, Senior Physician, HaEmek Medical Center, Israel
ClinicalTrials.gov Identifier: NCT01040247     History of Changes
Other Study ID Numbers: 0027-09-EMC 
Study First Received: December 28, 2009
Last Updated: June 21, 2015
Health Authority: Israel: Department of Health

Keywords provided by HaEmek Medical Center, Israel:
Infertility
Low Responder
IVF
Embryo Transfer

Additional relevant MeSH terms:
Infertility
Genital Diseases, Male
Genital Diseases, Female

ClinicalTrials.gov processed this record on August 23, 2016