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The Effect of Paravertebral Block Using a Multi-orifice Catheter on Preventing Acute and Chronic Post-thoracotomy Pain

This study has been completed.
Information provided by:
Seoul National University Hospital Identifier:
First received: December 23, 2009
Last updated: February 16, 2012
Last verified: February 2012
This study aims to evaluate the effect of the paravertebral block using a multi-lumen catheter on the incidence and severity of acute and chronic postthoracotomy pain compared to the thoracic epidural block.

Condition Intervention
Acute Postthoracotomy Pain
Chronic Postthoracotomy Pain
Hypotension After Bolus Dose
Procedure: paravertebral block
Procedure: thoracic epidural analgesia

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment

Further study details as provided by Seoul National University Hospital:

Primary Outcome Measures:
  • Incidence and severity of acute postthoracotomy pain when moving [ Time Frame: 24 hours after thoracotomy ]

Secondary Outcome Measures:
  • Incidence of chronic postthoracotomy pain [ Time Frame: 6 months after thoracotomy ]

Estimated Enrollment: 90
Study Start Date: July 2010
Study Completion Date: February 2012
Primary Completion Date: February 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: PVB
Paravertebral block initiated at the later part of thoracotomy is used for postoperative pain control
Procedure: paravertebral block
postoperative pain is controlled with local analgesics delivered via PVB
Active Comparator: TEA
Thoracic epidural block initiated before the surgical incision is used for postoperative pain control.
Procedure: thoracic epidural analgesia
postoperative pain is controlled with local analgesics and fentanyl delivered via thoracic epidural catheter


Ages Eligible for Study:   19 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • patients receiving surgery through a thoracotomy incision

Exclusion Criteria:

  • patients with cardiovascular disease
  • patients with neurologic disease
  • patients with contraindications to paravertebral block or epidural block
  • patients with history of previous thoracotomy incision
  • patients with pain at the expected incision site
  Contacts and Locations
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Please refer to this study by its identifier: NCT01039870

Korea, Republic of
Seoul National University Hospital
Seoul, Korea, Republic of, 110-744
Sponsors and Collaborators
Seoul National University Hospital
  More Information

Responsible Party: Young-Tae Kim, Seoul National University Hospital Identifier: NCT01039870     History of Changes
Other Study ID Numbers: YTKim_PVB_Postthor Pain
Study First Received: December 23, 2009
Last Updated: February 16, 2012

Keywords provided by Seoul National University Hospital:
postthoracotomy pain

Additional relevant MeSH terms:
Vascular Diseases
Cardiovascular Diseases processed this record on April 28, 2017