Vitamin D Levels and Postoperative Hypocalcemia After Total Thyroidectomy
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ClinicalTrials.gov Identifier: NCT01039714
Verified December 2009 by Aristotle University Of Thessaloniki. Recruitment status was: Recruiting
Hypocalcemia is one of the most frequent complications of total thyroidectomy, a procedure used for benign as well as malignant conditions of the thyroid gland. Postoperative hypocalcemia is usually caused by hypoparathyroidism. Vitamin D is implicated in calcium metabolism as it increases intestinal calcium transport and regulates parathormone production. Aim of the present study is to evaluate preoperative vitamin D levels as a prognostic factor for postoperative hypocalcemia and hypoparathyroidism.
Condition or disease
HypocalcemiaHypoparathyroidismVitamin D DeficiencyThyroidectomy
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients subjected to total thyroidectomy in Third Surgical Clinic of AHEPA University Hospital
Patient is over 18 years old
Patient scheduled for total thyroidectomy
Patient signs and dates a written informed consent form (ICF) and indicates an understanding of the study procedures
Chronic Renal Failure
Systematic Diseases (e.g., infections)
Thyroid or parathyroid cancer
Drugs that influence calcium metabolism (vitamin D analogues, oral calcium supplements, biphosphonates, teriparatide, thiazide diuretics)