QuantiFERON Change During Anti-tuberculosis Medication

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01038830
Recruitment Status : Completed
First Posted : December 24, 2009
Last Update Posted : June 14, 2010
Information provided by:
Armed Forces Capital Hospital, Republic of Korea

Brief Summary:
The aim of this study is to evaluate the change of QuantiFERON-TB gold in tube assay (QFT) during the treatment of active tuberculosis.

Condition or disease
Tuberculosis Interferon-gamma Release Assay

Detailed Description:
Patients with active pulmonary tuberculosis are enrolled and, QFTs are performed for each subjects before treatment and 1, 3, 6 months after treatment. Investigators check the level of interferon-gamma, and reversion and conversion of this test.

Study Type : Observational
Estimated Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Change in Level of Interferon-gamma Assay in Active Tuberculosis Patients During Treatment
Study Start Date : May 2008
Actual Primary Completion Date : April 2010
Actual Study Completion Date : May 2010

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Tuberculosis

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Young healthy subjects in Korean military

Inclusion Criteria:

  • All subjects with active tuberculosis

Exclusion Criteria:

  • Subjects who cannot complete study
  • Subjects who have taken anti-tuberculosis medication for more than a month before visit of our hospital

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01038830

Korea, Republic of
Armed Forces Capital Hospital
Seongnam, Gyeonggi-do, Korea, Republic of, 463-040
Sponsors and Collaborators
Armed Forces Capital Hospital, Republic of Korea

Responsible Party: Sei Won Lee/Division chief of pulmonology, Armed Forces Capital Hospital Identifier: NCT01038830     History of Changes
Other Study ID Numbers: QFTchange
First Posted: December 24, 2009    Key Record Dates
Last Update Posted: June 14, 2010
Last Verified: December 2009

Additional relevant MeSH terms:
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections