Mindfulness Based Cognitive Therapy for Recurrent Depression
Recruitment status was Active, not recruiting
The purpose of this study is to investigate the effectiveness and possible mediating factors of Mindfulness Based Cognitive Therapy (MBCT) for recurrent depression.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Mindfulness Based Cognitive Therapy for Patients With Recurrent Depression: a Clinical Trial|
- Relapse/Recurrence of Major Depressive Episode [ Time Frame: 6, 9, 12, 15 months ] [ Designated as safety issue: No ]
- Psychiatric symptoms and mindfulness skills measured by questionnaires [ Time Frame: 0, 3, 6, 9, 12, 15 months ] [ Designated as safety issue: No ]
|Study Start Date:||January 2005|
|Estimated Study Completion Date:||January 2011|
|Estimated Primary Completion Date:||March 2010 (Final data collection date for primary outcome measure)|
Experimental: Mindfulness Based Cognitive Therapy
Mindfulness Based Cognitive Therapy
Behavioral: Mindfulness Based Cognitive Therapy
8-weeks group based intervention of mindfulness and cognitive behavioural techniques
Other Name: MBCT
No Intervention: Waiting list control group
3-month waiting list group
Mindfulness Based Cognitive Therapy (MBCT) is a 8 session group intervention and is well described by several authors.
Previous studies showed Mindfulness Based Cognitive Therapy (MBCT) to be effective to prevent relapse in patients with recurrent depression and 3 or more previous depressive episodes.
Study aims are:
- to replicate previous findings in The Netherlands, by a research team which did not develop the intervention
- to investigate if MBCT is applicable for patients with recurrent depression and current depressive symptoms
- to examine possible mediators of treatment effect and predictors of relapse in the year following the treatment
In this study, patients are randomly assigned to a MBCT intervention group or a waiting list control group. Patients allocated to the waiting list control condition will receive the MBCT course three months later. All patients who participated in a MBCT training will be assessed during the year following the completion of the MBCT course. We aim to include about 220 patients.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01038765
|Radboud University Nijmegen Medical Center|
|Nijmegen, Gelderland, Netherlands, 6525 GC|
|Principal Investigator:||Anne EM Speckens, Prof. dr.||Radboud University|