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Health2010-14: Monitoring Biomarkers of Chronic Diseases in the General Population (Health2010-4)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01038518
First Posted: December 24, 2009
Last Update Posted: January 22, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Steno Diabetes Centre, Gentofte, Denmark
Information provided by (Responsible Party):
Allan Linneberg, Glostrup University Hospital, Copenhagen
  Purpose
The overall aim of the Health2010-14 is to monitor the prevalence and trends of common chronic diseases (osteoporosis, diabetes, cardiovascular disease, asthma, allergy, and eczema) that are often un-diagnosed in the general population as well as biomarkers of micronutrient status. Specific aims include identification of novel lifestyle and genetic risk factors for the above diseases by investigating gene-lifestyle interactions.

Condition
Cardiovascular Disease Type 2 Diabetes Asthma Allergy Osteoporosis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Health2010-14: Monitoring Biomarkers of Chronic Diseases in the General Population

Resource links provided by NLM:


Further study details as provided by Allan Linneberg, Glostrup University Hospital, Copenhagen:

Primary Outcome Measures:
  • 5-year change in prevalence of biomarkers of chronic diseases (e.g. diabetes, asthma, allergy) and micronutrient status (e.g. vitamin D status). [ Time Frame: 5 years ]

Secondary Outcome Measures:
  • significant interaction (on a additive scale) between Vitamin D status and genetic variants in the Vitamin D receptor in relation to selected chronic disease biomarkers [ Time Frame: 5 years ]

Biospecimen Retention:   Samples With DNA
Urine, serum, whole blood, extracted DNA

Enrollment: 1522
Study Start Date: November 2010
Study Completion Date: August 2011
Primary Completion Date: August 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
Health2010
Cross-sectional general population study

Detailed Description:
Over a 5-year period a series of population-based studies are carried out including a total of up to 10,000 persons aged 18-69 years selected from the general population of Copenhagen, Denmark. The study also include a follow-up of a previous population study (the Health2006). Participants complete questionnaires on health, lifestyle, and social factors and undergo a health examination including measurements of metabolic biomarkers, allergy tests, anthropometric measures, bioimpedance, biomarkers of micronutrients, spirometry.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 72 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Random samples of persons living in 10 municipalities in the Western part of the Capital Region of Denmark (Copenhagen).
Criteria

Inclusion Criteria:

  • persons living in 10 municipalities of Copenhagen

Exclusion Criteria:

  • pregnancy, non-Danish citizenship
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01038518


Sponsors and Collaborators
Glostrup University Hospital, Copenhagen
Steno Diabetes Centre, Gentofte, Denmark
Investigators
Study Director: Allan Linneberg, MD, PhD Research Center for Prevention and Health, Glostrup Hospital
  More Information

Additional Information:
Responsible Party: Allan Linneberg, Professor, Head of Section, Glostrup University Hospital, Copenhagen
ClinicalTrials.gov Identifier: NCT01038518     History of Changes
Other Study ID Numbers: H2009124
First Submitted: December 22, 2009
First Posted: December 24, 2009
Last Update Posted: January 22, 2015
Last Verified: January 2015

Keywords provided by Allan Linneberg, Glostrup University Hospital, Copenhagen:
epidemiology
risk factors
micronutrients

Additional relevant MeSH terms:
Cardiovascular Diseases
Osteoporosis
Chronic Disease
Bone Diseases, Metabolic
Bone Diseases
Musculoskeletal Diseases
Metabolic Diseases
Disease Attributes
Pathologic Processes