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Health2010-14: Monitoring Biomarkers of Chronic Diseases in the General Population (Health2010-4)

This study has been completed.
Sponsor:
Collaborator:
Steno Diabetes Centre, Gentofte, Denmark
Information provided by (Responsible Party):
Allan Linneberg, Glostrup University Hospital, Copenhagen
ClinicalTrials.gov Identifier:
NCT01038518
First received: December 22, 2009
Last updated: January 21, 2015
Last verified: January 2015
  Purpose

The overall aim of the Health2010-14 is to monitor the prevalence and trends of common chronic diseases (osteoporosis, diabetes, cardiovascular disease, asthma, allergy, and eczema) that are often un-diagnosed in the general population as well as biomarkers of micronutrient status. Specific aims include identification of novel lifestyle and genetic risk factors for the above diseases by investigating gene-lifestyle interactions.


Condition
Cardiovascular Disease
Type 2 Diabetes
Asthma
Allergy
Osteoporosis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Health2010-14: Monitoring Biomarkers of Chronic Diseases in the General Population

Resource links provided by NLM:


Further study details as provided by Glostrup University Hospital, Copenhagen:

Primary Outcome Measures:
  • 5-year change in prevalence of biomarkers of chronic diseases (e.g. diabetes, asthma, allergy) and micronutrient status (e.g. vitamin D status). [ Time Frame: 5 years ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • significant interaction (on a additive scale) between Vitamin D status and genetic variants in the Vitamin D receptor in relation to selected chronic disease biomarkers [ Time Frame: 5 years ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Urine, serum, whole blood, extracted DNA


Enrollment: 1522
Study Start Date: November 2010
Study Completion Date: August 2011
Primary Completion Date: August 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
Health2010
Cross-sectional general population study

Detailed Description:

Over a 5-year period a series of population-based studies are carried out including a total of up to 10,000 persons aged 18-69 years selected from the general population of Copenhagen, Denmark. The study also include a follow-up of a previous population study (the Health2006). Participants complete questionnaires on health, lifestyle, and social factors and undergo a health examination including measurements of metabolic biomarkers, allergy tests, anthropometric measures, bioimpedance, biomarkers of micronutrients, spirometry.

  Eligibility

Ages Eligible for Study:   18 Years to 72 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Random samples of persons living in 10 municipalities in the Western part of the Capital Region of Denmark (Copenhagen).

Criteria

Inclusion Criteria:

  • persons living in 10 municipalities of Copenhagen

Exclusion Criteria:

  • pregnancy, non-Danish citizenship
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01038518

Sponsors and Collaborators
Glostrup University Hospital, Copenhagen
Steno Diabetes Centre, Gentofte, Denmark
Investigators
Study Director: Allan Linneberg, MD, PhD Research Center for Prevention and Health, Glostrup Hospital
  More Information

Additional Information:
No publications provided

Responsible Party: Allan Linneberg, Professor, Head of Section, Glostrup University Hospital, Copenhagen
ClinicalTrials.gov Identifier: NCT01038518     History of Changes
Other Study ID Numbers: H2009124
Study First Received: December 22, 2009
Last Updated: January 21, 2015
Health Authority: Denmark: The Regional Committee on Biomedical Research Ethics

Keywords provided by Glostrup University Hospital, Copenhagen:
epidemiology
risk factors
micronutrients

ClinicalTrials.gov processed this record on March 03, 2015