Progression to Impaired Glucose Tolerance and Type 2 Diabetes in the Korean People-based KNDP Study

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01034826
Recruitment Status : Completed
First Posted : December 18, 2009
Last Update Posted : June 9, 2010
Information provided by:
Korea University Guro Hospital

Brief Summary:
Impaired glucose tolerance is a metabolic state between normal glucose homeostasis and diabetes. Previously, prospective studies have shown higher progression rates from IGT to diabetes in other country. But There is no prospective-multicenter based reports in Korea. Therefore, the purpose of this study is to estimate the progression rates to impair glucose regulation and diabetes in the Korean population-based Korea national Diabetes program.

Condition or disease
Impaired Glucose Tolerance Diabetes

Study Type : Observational
Estimated Enrollment : 500 participants
Observational Model: Case-Only
Time Perspective: Prospective
Study Start Date : February 2007
Actual Primary Completion Date : December 2009
Actual Study Completion Date : May 2010

Resource links provided by the National Library of Medicine

U.S. FDA Resources

life style modification
everyone in this study was advised about their life style, diet, exercise habits.

Primary Outcome Measures :
  1. fasting serum glucose, fasting plasma insulin,post prandial serum glucose, post prandial plasma insulin, hbA1c [ Time Frame: year ]

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
patients who vist the endocrinology department due to impaired fasting glucose or impaired glucose tolerance, or both.

Inclusion Criteria:

  • fastic serum glucose >100 and/or pp2 serum glucose <200

Exclusion Criteria:

  • known diabetes
  • organ failure(For example, liver, kidney)
  • known malignancy

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Korea university Guro Hospital Endocrinology department, Korea university Identifier: NCT01034826     History of Changes
Other Study ID Numbers: KNDP IGT study
First Posted: December 18, 2009    Key Record Dates
Last Update Posted: June 9, 2010
Last Verified: December 2009

Keywords provided by Korea University Guro Hospital:
NGT, IGT, diabetes

Additional relevant MeSH terms:
Glucose Intolerance
Glucose Metabolism Disorders
Metabolic Diseases