Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes
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ClinicalTrials.gov Identifier: NCT01034527 |
Recruitment Status
:
Completed
First Posted
: December 17, 2009
Last Update Posted
: March 26, 2014
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
ACL Injury | Other: Neuromuscular Training Other: Speed Protocol | Not Applicable |

Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 593 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) |
Primary Purpose: | Prevention |
Official Title: | Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female |
Study Start Date : | June 2009 |
Actual Primary Completion Date : | June 2013 |
Actual Study Completion Date : | June 2013 |
Arm | Intervention/treatment |
---|---|
Experimental: Neuromuscular Training
Combination of exercises and phases designed to initiate lateral trunk perturbations that force the athlete to decelerate and control the trunk in order to successfully perform the techniques.
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Other: Neuromuscular Training
Combination of exercises and phases to initiate lateral trunk perturbations that force the athlete to decelerate and control the trunk in order to successfully perform the techniques.
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Sham Comparator: Speed Training
Speed training protocol Sham training will consist of sagittal plane only running drills designs solely to enhance sprint speed. A sham sagittal plane sprint training protocol that will be instituted with the teams that are randomly selected for sham treatment. Five phases will be utilized to facilitate progressions designed to improve the athletes' forward sprinting speed. Training volume will be approximately equivalent for the TNMT and sham protocols. They each will take athletes approximately 30 minutes to complete
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Other: Speed Protocol
Sham training will consist of sagittal plane only running drills designs solely to enhance sprint speed. A sham sagittal plane sprint training protocol that will be instituted with the teams that are randomly selected for sham treatment. Five phases will be utilized to facilitate progressions designed to improve the athletes' forward sprinting speed. Training volume will be approximately equivalent for the TNMT and sham protocols. They each will take athletes approximately 30 minutes to complete
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- Optimize the effectiveness of interventions designed to prevent ACL injuries [ Time Frame: 2 years ]

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Ages Eligible for Study: | 10 Years to 19 Years (Child, Adult) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Female
- Soccer, Basketball, or Volleyball athlete
- Attends Middle School or High School in Boone County or Fayette County KY
Exclusion Criteria:
- Male

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01034527
United States, Ohio | |
Cincinnati Children's Hospital Medical Center | |
Cincinnati, Ohio, United States, 45206 |
Principal Investigator: | Timothy E Hewett, Phd | Children's Hospital Medical Center, Cincinnati | |
Study Director: | Kim D Barber Foss, MS | Children's Hospital Medical Center, Cincinnati | |
Study Director: | Staci Thomas, Ms | Children's Hospital Medical Center, Cincinnati |
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Children's Hospital Medical Center, Cincinnati |
ClinicalTrials.gov Identifier: | NCT01034527 History of Changes |
Other Study ID Numbers: |
2009-0602 5R01AR055563 ( U.S. NIH Grant/Contract ) |
First Posted: | December 17, 2009 Key Record Dates |
Last Update Posted: | March 26, 2014 |
Last Verified: | March 2014 |
Keywords provided by Children's Hospital Medical Center, Cincinnati:
Anterior Cruciate Ligament Female Athlete Sports Injuries Injury Prevention |
Additional relevant MeSH terms:
Anterior Cruciate Ligament Injuries Knee Injuries Leg Injuries Wounds and Injuries Methamphetamine Central Nervous System Stimulants Physiological Effects of Drugs Sympathomimetics Autonomic Agents |
Peripheral Nervous System Agents Dopamine Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Adrenergic Agents Adrenergic Uptake Inhibitors Neurotransmitter Uptake Inhibitors Membrane Transport Modulators Dopamine Uptake Inhibitors |