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Bioactive Milk Peptides and Blood Pressure

This study has been completed.
Helsinki University
Information provided by:
Valio Ltd Identifier:
First received: December 11, 2009
Last updated: December 19, 2014
Last verified: December 2009
The purpose of this study is to investigate the effects of bioactive milk peptides on blood pressure in mildly hypertensive subjects.

Condition Intervention Phase
Stage 1 Hypertension Dietary Supplement: Milk peptides and plant sterols Other: Placebo Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double

Further study details as provided by Valio Ltd:

Primary Outcome Measures:
  • Blood pressure

Study Start Date: January 2010
Study Completion Date: August 2010
Primary Completion Date: June 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Spread with milk peptides and plant sterols Dietary Supplement: Milk peptides and plant sterols
Placebo Comparator: Standard spread Other: Placebo


Ages Eligible for Study:   30 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • age 30-60 years
  • systolic blood pressure 140-160 mmHg and diastolic blood pressure 90-99 mmHg in office measurement
  • apparently healthy

Exclusion Criteria:

  • antihypertensive and lipid-lowering drugs
  • unstable coronary artery disease, diabetes, malignant diseases, secondary hypertension
  • BMI > 32 kg/m2
  • milk allergy
  • smoking
  • alcohol abuse
  • pregnancy, lactation
  • simultaneous participation in other clinical trial
  Contacts and Locations
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Please refer to this study by its identifier: NCT01031485

Valio Ltd
Helsinki, Uusimaa, Finland, 00370
Sponsors and Collaborators
Valio Ltd
Helsinki University
  More Information Identifier: NCT01031485     History of Changes
Other Study ID Numbers: Valio-70
Study First Received: December 11, 2009
Last Updated: December 19, 2014

Keywords provided by Valio Ltd:
blood pressure
milk peptides
bioactive peptides
randomized controlled trial

Additional relevant MeSH terms:
Vascular Diseases
Cardiovascular Diseases processed this record on August 18, 2017